U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from Nucleotide

    • Showing Current items.

    NCK2 NCK adaptor protein 2 [ Talpa occidentalis (Iberian mole) ]

    Gene ID: 119259291, updated on 21-Mar-2024

    Summary

    Go to the top of the page Help
    Gene symbol
    NCK2
    Gene description
    NCK adaptor protein 2
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Talpa occidentalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Eulipotyphla; Talpidae; Talpa
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See NCK2 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2023_03 current MPIMG_talOcc4v2.1 (GCF_014898055.3) Unplaced Scaffold NW_023604861.1 (105001180..105111692)

    NW_023604861.1Genomic Context describing neighboring genes Neighboring gene chromosome unknown C2orf49 homolog Neighboring gene uncharacterized LOC119259290 Neighboring gene four and a half LIM domains 2 Neighboring gene ECRG4 augurin precursor Neighboring gene UDP-glucuronate decarboxylase 1

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NW_023604861 Unplaced Scaffold Reference MPIMG_talOcc4v2.1 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of PERK-mediated unfolded protein response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of translation in response to endoplasmic reticulum stress IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    cytoplasmic protein NCK2

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_014898055.3-RS_2023_03

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference MPIMG_talOcc4v2.1 Primary Assembly

    Genomic

    1. NW_023604861.1 Reference MPIMG_talOcc4v2.1 Primary Assembly

      Range
      105001180..105111692
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_037528041.2 → XP_037383938.1  cytoplasmic protein NCK2

      Conserved Domains (4) summary
      cd10409
      Location:283 → 380
      SH2_Nck2; Src homology 2 (SH2) domain found in Nck
      cd11899
      Location:2 → 59
      SH3_Nck2_1; First Src Homology 3 domain of Nck2 adaptor protein
      cd11902
      Location:114 → 168
      SH3_Nck2_2; Second Src Homology 3 domain of Nck2 adaptor protein
      cd11903
      Location:198 → 256
      SH3_Nck2_3; Third Src Homology 3 domain of Nck2 adaptor protein

    2. XM_037528048.2 → XP_037383945.1  cytoplasmic protein NCK2

      Conserved Domains (4) summary
      cd10409
      Location:283 → 380
      SH2_Nck2; Src homology 2 (SH2) domain found in Nck
      cd11899
      Location:2 → 59
      SH3_Nck2_1; First Src Homology 3 domain of Nck2 adaptor protein
      cd11902
      Location:114 → 168
      SH3_Nck2_2; Second Src Homology 3 domain of Nck2 adaptor protein
      cd11903
      Location:198 → 256
      SH3_Nck2_3; Third Src Homology 3 domain of Nck2 adaptor protein

    3. XM_037528043.2 → XP_037383940.1  cytoplasmic protein NCK2

      Conserved Domains (4) summary
      cd10409
      Location:283 → 380
      SH2_Nck2; Src homology 2 (SH2) domain found in Nck
      cd11899
      Location:2 → 59
      SH3_Nck2_1; First Src Homology 3 domain of Nck2 adaptor protein
      cd11902
      Location:114 → 168
      SH3_Nck2_2; Second Src Homology 3 domain of Nck2 adaptor protein
      cd11903
      Location:198 → 256
      SH3_Nck2_3; Third Src Homology 3 domain of Nck2 adaptor protein

    4. XM_037528042.2 → XP_037383939.1  cytoplasmic protein NCK2

      Conserved Domains (4) summary
      cd10409
      Location:283 → 380
      SH2_Nck2; Src homology 2 (SH2) domain found in Nck
      cd11899
      Location:2 → 59
      SH3_Nck2_1; First Src Homology 3 domain of Nck2 adaptor protein
      cd11902
      Location:114 → 168
      SH3_Nck2_2; Second Src Homology 3 domain of Nck2 adaptor protein
      cd11903
      Location:198 → 256
      SH3_Nck2_3; Third Src Homology 3 domain of Nck2 adaptor protein

    5. XM_037528044.2 → XP_037383941.1  cytoplasmic protein NCK2

      Conserved Domains (4) summary
      cd10409
      Location:283 → 380
      SH2_Nck2; Src homology 2 (SH2) domain found in Nck
      cd11899
      Location:2 → 59
      SH3_Nck2_1; First Src Homology 3 domain of Nck2 adaptor protein
      cd11902
      Location:114 → 168
      SH3_Nck2_2; Second Src Homology 3 domain of Nck2 adaptor protein
      cd11903
      Location:198 → 256
      SH3_Nck2_3; Third Src Homology 3 domain of Nck2 adaptor protein

    6. XM_054701990.1 → XP_054557965.1  cytoplasmic protein NCK2

    7. XM_054701991.1 → XP_054557966.1  cytoplasmic protein NCK2

    8. XM_037528045.2 → XP_037383942.1  cytoplasmic protein NCK2

      Conserved Domains (4) summary
      cd10409
      Location:283 → 380
      SH2_Nck2; Src homology 2 (SH2) domain found in Nck
      cd11899
      Location:2 → 59
      SH3_Nck2_1; First Src Homology 3 domain of Nck2 adaptor protein
      cd11902
      Location:114 → 168
      SH3_Nck2_2; Second Src Homology 3 domain of Nck2 adaptor protein
      cd11903
      Location:198 → 256
      SH3_Nck2_3; Third Src Homology 3 domain of Nck2 adaptor protein

    9. XM_037528047.2 → XP_037383944.1  cytoplasmic protein NCK2

      Conserved Domains (4) summary
      cd10409
      Location:283 → 380
      SH2_Nck2; Src homology 2 (SH2) domain found in Nck
      cd11899
      Location:2 → 59
      SH3_Nck2_1; First Src Homology 3 domain of Nck2 adaptor protein
      cd11902
      Location:114 → 168
      SH3_Nck2_2; Second Src Homology 3 domain of Nck2 adaptor protein
      cd11903
      Location:198 → 256
      SH3_Nck2_3; Third Src Homology 3 domain of Nck2 adaptor protein
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.