U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from Nucleotide

    • Showing Current items.

    PLEKHH2 pleckstrin homology, MyTH4 and FERM domain containing H2 [ Talpa occidentalis (Iberian mole) ]

    Gene ID: 119259359, updated on 21-Mar-2024

    Summary

    Go to the top of the page Help
    Gene symbol
    PLEKHH2
    Gene description
    pleckstrin homology, MyTH4 and FERM domain containing H2
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Talpa occidentalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Eulipotyphla; Talpidae; Talpa
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See PLEKHH2 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    30
    Annotation release Status Assembly Chr Location
    RS_2023_03 current MPIMG_talOcc4v2.1 (GCF_014898055.3) Unplaced Scaffold NW_023604861.1 (113652199..113721180, complement)

    NW_023604861.1Genomic Context describing neighboring genes Neighboring gene ATP binding cassette subfamily G member 5 Neighboring gene dynein cytoplasmic 2 light intermediate chain 1 Neighboring gene 60S ribosomal protein L29-like Neighboring gene THADA armadillo repeat containing Neighboring gene GTP-binding protein SAR1b-like

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NW_023604861 Unplaced Scaffold Reference MPIMG_talOcc4v2.1 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables actin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of actin filament depolymerization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    pleckstrin homology domain-containing family H member 2

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_014898055.3-RS_2023_03

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference MPIMG_talOcc4v2.1 Primary Assembly

    Genomic

    1. NW_023604861.1 Reference MPIMG_talOcc4v2.1 Primary Assembly

      Range
      113652199..113721180 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_037528149.2 → XP_037384046.1  pleckstrin homology domain-containing family H member 2 isoform X1

      Conserved Domains (8) summary
      PTZ00121
      Location:3 → 389
      PTZ00121; MAEBL; Provisional
      smart00139
      Location:954 → 1109
      MyTH4; Domain in Myosin and Kinesin Tails
      smart00295
      Location:1122 → 1353
      B41; Band 4.1 homologues
      COG1196
      Location:19 → 181
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd13206
      Location:1349 → 1448
      FERM_C-lobe_PLEKHH1_PLEKHH2; FERM domain C-lobe of Pleckstrin homology domain-containing family H
      cd13282
      Location:705 → 800
      PH1_PLEKHH1_PLEKHH2; Pleckstrin homology (PH) domain containing, family H (with MyTH4 domain) members 1 and 2 (PLEKHH1) PH domain, repeat 1
      cd17179
      Location:1119 → 1221
      FERM_F1_PLEKHH2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in pleckstrin homology domain-containing family H member 2 (PLEKHH2)
      cl17171
      Location:815 → 872
      PH-like; Pleckstrin homology-like domain

    2. XM_037528150.1 → XP_037384047.1  pleckstrin homology domain-containing family H member 2 isoform X2

      Conserved Domains (6) summary
      PTZ00121
      Location:3 → 389
      PTZ00121; MAEBL; Provisional
      smart00139
      Location:954 → 1109
      MyTH4; Domain in Myosin and Kinesin Tails
      COG1196
      Location:19 → 181
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd13282
      Location:705 → 800
      PH1_PLEKHH1_PLEKHH2; Pleckstrin homology (PH) domain containing, family H (with MyTH4 domain) members 1 and 2 (PLEKHH1) PH domain, repeat 1
      cl17171
      Location:815 → 872
      PH-like; Pleckstrin homology-like domain
      cl28922
      Location:1119 → 1205
      Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.