MINK1 misshapen like kinase 1 [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: MINK1provided by VGNC
Official Full Name: misshapen like kinase 1provided by VGNC
Primary source: VGNC:VGNC:31479
See related: BGD:BT11824; Ensembl:ENSBTAG00000004907
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as: MINK
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 19

Exon count:: 34

Annotation release	Status	Assembly	Chr	Location
RS_2024_12	current	ARS-UCD2.0 (GCF_002263795.3)	19	NC_037346.1 (26489827..26536886, complement)

Chromosome 19 - NC_037346.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037346.1 Chromosome 19 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Dominette sequence data
BioProject: PRJNA294306
Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

MARC_2911-2912:991933702:1 (e-PCR)
- UniSTS:230976

MARC_21871-21872:1046872408:1 (e-PCR)
- UniSTS:268659

MARC_1869-1870:991931535:1 (e-PCR)
- UniSTS:230877

G09516 (e-PCR)
- UniSTS:30707

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables protein kinase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in protein phosphorylation	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: misshapen-like kinase 1

Names: GCK family kinase

NP_001092846.1

EC 2.7.11.1

XP_024835908.1

EC 2.7.11.1

XP_024835909.1

EC 2.7.11.1

XP_024835910.1

EC 2.7.11.1

XP_024835911.1

EC 2.7.11.1

XP_024835912.1

EC 2.7.11.1

XP_024835913.1

EC 2.7.11.1

XP_024835914.1

EC 2.7.11.1

XP_024835915.1

EC 2.7.11.1

XP_024835916.1

EC 2.7.11.1

XP_024835917.1

EC 2.7.11.1

XP_024835918.1

EC 2.7.11.1

XP_024835919.1

EC 2.7.11.1

XP_024835920.1

EC 2.7.11.1

XP_024835921.1

EC 2.7.11.1

XP_024835922.1

EC 2.7.11.1

XP_024835923.1

EC 2.7.11.1

XP_024835924.1

EC 2.7.11.1

XP_024835925.1

EC 2.7.11.1

XP_024835926.1

EC 2.7.11.1

XP_024835927.1

EC 2.7.11.1

XP_024835928.1

EC 2.7.11.1

XP_024835929.1

EC 2.7.11.1

XP_024835930.1

EC 2.7.11.1

XP_024835931.1

EC 2.7.11.1

XP_024835932.1

EC 2.7.11.1

XP_024835933.1

EC 2.7.11.1

XP_024835934.1

EC 2.7.11.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001099376.1 → NP_001092846.1 misshapen-like kinase 1

See identical proteins and their annotated locations for NP_001092846.1

Status: PROVISIONAL

Source sequence(s)

BC146263

UniProtKB/TrEMBL

A0A3Q1LTD6, A6H7I9

Related

ENSBTAP00000058419.2, ENSBTAT00000078526.2

Conserved Domains (3) summary

smart00036
Location:992 → 1290

CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2

smart00220
Location:25 → 289

S_TKc; Serine/Threonine protein kinases, catalytic domain

cd06636
Location:8 → 289

STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

NC_037346.1 Reference ARS-UCD2.0 Primary Assembly

Range

26489827..26536886 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_024980166.2 → XP_024835934.1 misshapen-like kinase 1 isoform X27

UniProtKB/TrEMBL

A0A3Q1LTD6

Conserved Domains (3) summary

smart00036
Location:955 → 1253

CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2

cd06636
Location:8 → 289

STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6

cl28033
Location:538 → 743

Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region
XM_024980165.2 → XP_024835933.1 misshapen-like kinase 1 isoform X26

UniProtKB/TrEMBL

A0A3Q1LTD6

Conserved Domains (3) summary

smart00036
Location:956 → 1254

CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2

cd06636
Location:8 → 289

STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6

cl28033
Location:538 → 743

Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region
XM_024980164.2 → XP_024835932.1 misshapen-like kinase 1 isoform X25

UniProtKB/TrEMBL

A0A3Q1LTD6

Conserved Domains (3) summary

smart00036
Location:963 → 1261

CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2

cd06636
Location:8 → 289

STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6

cl28033
Location:538 → 743

Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region
XM_024980163.2 → XP_024835931.1 misshapen-like kinase 1 isoform X24

UniProtKB/TrEMBL

A0A3Q1LTD6

Conserved Domains (3) summary

smart00036
Location:964 → 1262

CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2

cd06636
Location:8 → 289

STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6

cl28033
Location:538 → 743

Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region
XM_024980156.2 → XP_024835924.1 misshapen-like kinase 1 isoform X17

UniProtKB/TrEMBL

A0A3Q1LTD6

Conserved Domains (3) summary

smart00036
Location:993 → 1291

CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2

cd06636
Location:8 → 289

STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6

cl28033
Location:538 → 799

Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region
XM_024980155.2 → XP_024835923.1 misshapen-like kinase 1 isoform X16

UniProtKB/TrEMBL

A0A3Q1LTD6

Conserved Domains (3) summary

smart00036
Location:1000 → 1298

CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2

cd06636
Location:8 → 289

STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6

cl28033
Location:538 → 780

Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region
XM_024980154.2 → XP_024835922.1 misshapen-like kinase 1 isoform X15

UniProtKB/TrEMBL

A0A3Q1LTD6

Conserved Domains (3) summary

smart00036
Location:1001 → 1299

CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2

cd06636
Location:8 → 289

STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6

cl28033
Location:538 → 780

Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region
XM_024980162.2 → XP_024835930.1 misshapen-like kinase 1 isoform X23

UniProtKB/TrEMBL

A0A3Q1LTD6

Conserved Domains (3) summary

smart00036
Location:975 → 1273

CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2

cd06636
Location:8 → 289

STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6

cl28033
Location:538 → 782

Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region
XM_024980161.2 → XP_024835929.1 misshapen-like kinase 1 isoform X22

UniProtKB/TrEMBL

A0A3Q1LTD6

Conserved Domains (3) summary

smart00036
Location:976 → 1274

CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2

cd06636
Location:8 → 289

STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6

cl28033
Location:538 → 782

Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region
XM_024980160.2 → XP_024835928.1 misshapen-like kinase 1 isoform X21

UniProtKB/TrEMBL

A0A3Q1LTD6

Conserved Domains (3) summary

smart00036
Location:983 → 1281

CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2

cd06636
Location:8 → 289

STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6

cl28033
Location:507 → 763

Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region
XM_024980159.2 → XP_024835927.1 misshapen-like kinase 1 isoform X20

UniProtKB/TrEMBL

A0A3Q1LTD6

Related

ENSBTAP00000063719.2, ENSBTAT00000087237.2

Conserved Domains (3) summary

smart00036
Location:984 → 1282

CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2

cd06636
Location:8 → 289

STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6

cl28033
Location:507 → 763

Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region
XM_024980150.2 → XP_024835918.1 misshapen-like kinase 1 isoform X11

UniProtKB/TrEMBL

A0A3Q1LTD6

Conserved Domains (3) summary

smart00036
Location:1012 → 1310

CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2

cd06636
Location:8 → 289

STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6

cl28033
Location:507 → 819

Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region
XM_024980148.2 → XP_024835916.1 misshapen-like kinase 1 isoform X9

UniProtKB/TrEMBL

A0A3Q1LKG0, A0A3Q1LTD6

Related

ENSBTAP00000057130.2, ENSBTAT00000077655.2

Conserved Domains (3) summary

smart00036
Location:1013 → 1311

CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2

cd06636
Location:8 → 289

STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6

cl28033
Location:507 → 819

Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region
XM_024980147.2 → XP_024835915.1 misshapen-like kinase 1 isoform X8

UniProtKB/TrEMBL

A0A3Q1LTD6

Conserved Domains (3) summary

smart00036
Location:1020 → 1318

CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2

cd06636
Location:8 → 289

STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6

cl28033
Location:507 → 800

Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region
XM_024980146.2 → XP_024835914.1 misshapen-like kinase 1 isoform X7

UniProtKB/TrEMBL

A0A3Q1LTD6, F6Q3P6

Related

ENSBTAP00000017318.7, ENSBTAT00000017318.7

Conserved Domains (3) summary

smart00036
Location:1021 → 1319

CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2

cd06636
Location:8 → 289

STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6

cl28033
Location:507 → 800

Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region
XM_024980158.2 → XP_024835926.1 misshapen-like kinase 1 isoform X19

UniProtKB/TrEMBL

A0A3Q1LTD6

Conserved Domains (3) summary

smart00036
Location:985 → 1283

CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2

cd06636
Location:8 → 289

STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6

cl28033
Location:567 → 772

Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region
XM_024980157.2 → XP_024835925.1 misshapen-like kinase 1 isoform X18

UniProtKB/TrEMBL

A0A3Q1LTD6

Conserved Domains (3) summary

smart00036
Location:992 → 1290

CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2

cd06636
Location:8 → 289

STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6

cl28033
Location:567 → 772

Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region
XM_024980145.2 → XP_024835913.1 misshapen-like kinase 1 isoform X6

UniProtKB/TrEMBL

A0A3Q1LTD6

Conserved Domains (3) summary

smart00036
Location:1029 → 1327

CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2

cd06636
Location:8 → 289

STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6

cl28033
Location:567 → 809

Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region
XM_024980144.2 → XP_024835912.1 misshapen-like kinase 1 isoform X5

UniProtKB/TrEMBL

A0A3Q1LTD6

Conserved Domains (3) summary

smart00036
Location:1030 → 1328

CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2

cd06636
Location:8 → 289

STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6

cl28033
Location:567 → 809

Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region
XM_024980153.2 → XP_024835921.1 misshapen-like kinase 1 isoform X14

UniProtKB/TrEMBL

A0A3Q1LTD6

Conserved Domains (3) summary

smart00036
Location:1004 → 1302

CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2

cd06636
Location:8 → 289

STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6

cl28033
Location:567 → 811

Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region
XM_024980152.2 → XP_024835920.1 misshapen-like kinase 1 isoform X13

UniProtKB/TrEMBL

A0A3Q1LTD6

Conserved Domains (3) summary

smart00036
Location:1005 → 1303

CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2

cd06636
Location:8 → 289

STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6

cl28033
Location:567 → 811

Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region
XM_024980151.2 → XP_024835919.1 misshapen-like kinase 1 isoform X12

UniProtKB/TrEMBL

A0A3Q1LTD6

Conserved Domains (3) summary

smart00036
Location:1012 → 1310

CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2

cd06636
Location:8 → 289

STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6

cl28033
Location:536 → 792

Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region
XM_024980149.2 → XP_024835917.1 misshapen-like kinase 1 isoform X10

UniProtKB/TrEMBL

A0A3Q1LTD6

Conserved Domains (3) summary

smart00036
Location:1013 → 1311

CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2

cd06636
Location:8 → 289

STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6

cl28033
Location:536 → 792

Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region
XM_024980143.2 → XP_024835911.1 misshapen-like kinase 1 isoform X4

UniProtKB/TrEMBL

A0A3Q1LTD6

Conserved Domains (3) summary

smart00036
Location:1041 → 1339

CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2

cd06636
Location:8 → 289

STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6

cl28033
Location:536 → 848

Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region
XM_024980142.2 → XP_024835910.1 misshapen-like kinase 1 isoform X3

UniProtKB/TrEMBL

A0A3Q1LTD6

Conserved Domains (3) summary

smart00036
Location:1042 → 1340

CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2

cd06636
Location:8 → 289

STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6

cl28033
Location:536 → 848

Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region
XM_024980141.2 → XP_024835909.1 misshapen-like kinase 1 isoform X2

UniProtKB/TrEMBL

A0A3Q1LTD6

Conserved Domains (3) summary

smart00036
Location:1049 → 1347

CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2

cd06636
Location:8 → 289

STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6

cl28033
Location:536 → 829

Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region
XM_024980140.2 → XP_024835908.1 misshapen-like kinase 1 isoform X1

UniProtKB/TrEMBL

A0A3Q1LTD6

Conserved Domains (3) summary

smart00036
Location:1050 → 1348

CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2

cd06636
Location:8 → 289

STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6

cl28033
Location:536 → 829

Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region