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    MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 [ Bos taurus (domestic cattle) ]

    Gene ID: 537598, updated on 27-Dec-2024

    Summary

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    Official Symbol
    MAPK8IP3provided by VGNC
    Official Full Name
    mitogen-activated protein kinase 8 interacting protein 3provided by VGNC
    Primary source
    VGNC:VGNC:31226
    See related
    BGD:BT20113; Ensembl:ENSBTAG00000002211
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
    NEW
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    Genomic context

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    See MAPK8IP3 in Genome Data Viewer
    Location:
    chromosome: 25
    Exon count:
    34
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 25 NC_037352.1 (1305496..1349468)

    Chromosome 25 - NC_037352.1Genomic Context describing neighboring genes Neighboring gene cramped chromatin regulator homolog 1 Neighboring gene Jupiter microtubule associated homolog 2 Neighboring gene mitochondrial ribosomal protein S34 Neighboring gene NME/NM23 nucleoside diphosphate kinase 3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037352.1 Chromosome 25 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables JUN kinase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables MAP-kinase scaffold activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables kinesin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables signaling receptor complex adaptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    C-Jun-amino-terminal kinase-interacting protein 3

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001076096.3 → NP_001069564.2  C-Jun-amino-terminal kinase-interacting protein 3

      See identical proteins and their annotated locations for NP_001069564.2

      Status: VALIDATED

      Source sequence(s)
      NKLS02000025
      UniProtKB/TrEMBL
      A0A3Q1LQI8, A0A8J8Y2F9, M5FKI5
      Conserved Domains (5) summary
      pfam05887
      Location:842 → 961
      Trypan_PARP; Procyclic acidic repetitive protein (PARP)
      pfam05103
      Location:38 → 167
      DivIVA; DivIVA protein
      pfam09744
      Location:30 → 183
      Jnk-SapK_ap_N; JNK_SAPK-associated protein-1
      pfam16471
      Location:409 → 477
      JIP_LZII; JNK-interacting protein leucine zipper II
      cl23720
      Location:424 → 537
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037352.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      1305496..1349468
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_010819109.3 → XP_010817411.1  C-Jun-amino-terminal kinase-interacting protein 3 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1MTK3, A0A8J8XE10, M5FMW2
      Conserved Domains (5) summary
      pfam05887
      Location:887 → 1006
      Trypan_PARP; Procyclic acidic repetitive protein (PARP)
      pfam05103
      Location:38 → 167
      DivIVA; DivIVA protein
      pfam09744
      Location:30 → 183
      Jnk-SapK_ap_N; JNK_SAPK-associated protein-1
      pfam16471
      Location:454 → 522
      JIP_LZII; JNK-interacting protein leucine zipper II
      cl23720
      Location:469 → 582
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

    2. XM_010819115.4 → XP_010817417.1  C-Jun-amino-terminal kinase-interacting protein 3 isoform X5

      UniProtKB/TrEMBL
      A0A3Q1MTK3, A0A8J8XE10, M5FMW2
      Conserved Domains (5) summary
      pfam05887
      Location:878 → 997
      Trypan_PARP; Procyclic acidic repetitive protein (PARP)
      pfam05103
      Location:38 → 167
      DivIVA; DivIVA protein
      pfam09744
      Location:30 → 183
      Jnk-SapK_ap_N; JNK_SAPK-associated protein-1
      pfam16471
      Location:454 → 522
      JIP_LZII; JNK-interacting protein leucine zipper II
      cl23720
      Location:469 → 582
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

    3. XM_010819114.3 → XP_010817416.1  C-Jun-amino-terminal kinase-interacting protein 3 isoform X7

      UniProtKB/TrEMBL
      A0A3Q1MTK3, A0A8J8XE10, M5FMW2
      Conserved Domains (4) summary
      pfam05887
      Location:878 → 997
      Trypan_PARP; Procyclic acidic repetitive protein (PARP)
      pfam05103
      Location:38 → 167
      DivIVA; DivIVA protein
      pfam09744
      Location:30 → 183
      Jnk-SapK_ap_N; JNK_SAPK-associated protein-1
      pfam16471
      Location:454 → 522
      JIP_LZII; JNK-interacting protein leucine zipper II

    4. XM_010819111.3 → XP_010817413.1  C-Jun-amino-terminal kinase-interacting protein 3 isoform X3

      UniProtKB/TrEMBL
      A0A3Q1LQI8, A0A8J8Y2F9, M5FKI5
      Conserved Domains (5) summary
      pfam05887
      Location:881 → 1000
      Trypan_PARP; Procyclic acidic repetitive protein (PARP)
      pfam05103
      Location:38 → 167
      DivIVA; DivIVA protein
      pfam09744
      Location:30 → 183
      Jnk-SapK_ap_N; JNK_SAPK-associated protein-1
      pfam16471
      Location:448 → 516
      JIP_LZII; JNK-interacting protein leucine zipper II
      cl23720
      Location:463 → 576
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

    5. XM_005224529.5 → XP_005224586.1  C-Jun-amino-terminal kinase-interacting protein 3 isoform X8

      UniProtKB/TrEMBL
      A0A3Q1MTK3, A0A8J8XE10, M5FMW2
      Related
      ENSBTAP00000057999.2, ENSBTAT00000078567.2
      Conserved Domains (5) summary
      pfam05887
      Location:857 → 976
      Trypan_PARP; Procyclic acidic repetitive protein (PARP)
      pfam05103
      Location:38 → 167
      DivIVA; DivIVA protein
      pfam09744
      Location:30 → 183
      Jnk-SapK_ap_N; JNK_SAPK-associated protein-1
      pfam16471
      Location:424 → 492
      JIP_LZII; JNK-interacting protein leucine zipper II
      cl23720
      Location:439 → 552
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

    6. XM_005224536.4 → XP_005224593.1  C-Jun-amino-terminal kinase-interacting protein 3 isoform X14

      UniProtKB/TrEMBL
      A0A3Q1LQI8, A0A8J8Y2F9, M5FKI5
      Related
      ENSBTAP00000062446.2, ENSBTAT00000067975.2
      Conserved Domains (5) summary
      pfam05887
      Location:847 → 966
      Trypan_PARP; Procyclic acidic repetitive protein (PARP)
      pfam05103
      Location:38 → 167
      DivIVA; DivIVA protein
      pfam09744
      Location:30 → 183
      Jnk-SapK_ap_N; JNK_SAPK-associated protein-1
      pfam16471
      Location:414 → 482
      JIP_LZII; JNK-interacting protein leucine zipper II
      cl23720
      Location:429 → 542
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

    7. XM_010819116.3 → XP_010817418.1  C-Jun-amino-terminal kinase-interacting protein 3 isoform X9

      UniProtKB/TrEMBL
      A0A3Q1MTK3, A0A8J8XE10, M5FMW2
      Conserved Domains (5) summary
      pfam05887
      Location:856 → 975
      Trypan_PARP; Procyclic acidic repetitive protein (PARP)
      pfam05103
      Location:38 → 167
      DivIVA; DivIVA protein
      pfam09744
      Location:30 → 183
      Jnk-SapK_ap_N; JNK_SAPK-associated protein-1
      pfam16471
      Location:423 → 491
      JIP_LZII; JNK-interacting protein leucine zipper II
      cl23720
      Location:438 → 551
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

    8. XM_010819121.3 → XP_010817423.1  C-Jun-amino-terminal kinase-interacting protein 3 isoform X17

      UniProtKB/TrEMBL
      A0A3Q1MTK3, A0A8J8XE10, M5FMW2
      Conserved Domains (5) summary
      pfam05887
      Location:826 → 945
      Trypan_PARP; Procyclic acidic repetitive protein (PARP)
      pfam05103
      Location:38 → 167
      DivIVA; DivIVA protein
      pfam09744
      Location:30 → 183
      Jnk-SapK_ap_N; JNK_SAPK-associated protein-1
      pfam16471
      Location:393 → 461
      JIP_LZII; JNK-interacting protein leucine zipper II
      cl23720
      Location:408 → 521
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

    9. XM_010819110.3 → XP_010817412.1  C-Jun-amino-terminal kinase-interacting protein 3 isoform X2

      UniProtKB/TrEMBL
      A0A3Q1MTK3, A0A8J8XE10, M5FMW2
      Conserved Domains (5) summary
      pfam05887
      Location:886 → 1005
      Trypan_PARP; Procyclic acidic repetitive protein (PARP)
      pfam05103
      Location:38 → 167
      DivIVA; DivIVA protein
      pfam09744
      Location:30 → 183
      Jnk-SapK_ap_N; JNK_SAPK-associated protein-1
      pfam16471
      Location:453 → 521
      JIP_LZII; JNK-interacting protein leucine zipper II
      cl23720
      Location:468 → 581
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

    10. XM_010819117.3 → XP_010817419.1  C-Jun-amino-terminal kinase-interacting protein 3 isoform X10

      UniProtKB/TrEMBL
      A0A3Q1MTK3, A0A8J8XE10, M5FMW2
      Conserved Domains (5) summary
      pfam05887
      Location:855 → 974
      Trypan_PARP; Procyclic acidic repetitive protein (PARP)
      pfam05103
      Location:38 → 167
      DivIVA; DivIVA protein
      pfam09744
      Location:30 → 183
      Jnk-SapK_ap_N; JNK_SAPK-associated protein-1
      pfam16471
      Location:422 → 490
      JIP_LZII; JNK-interacting protein leucine zipper II
      cl23720
      Location:437 → 550
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

    11. XM_010819112.3 → XP_010817414.1  C-Jun-amino-terminal kinase-interacting protein 3 isoform X4

      UniProtKB/TrEMBL
      A0A3Q1MTK3, A0A8J8XE10, M5FMW2
      Conserved Domains (5) summary
      pfam05887
      Location:879 → 998
      Trypan_PARP; Procyclic acidic repetitive protein (PARP)
      pfam05103
      Location:38 → 167
      DivIVA; DivIVA protein
      pfam09744
      Location:30 → 183
      Jnk-SapK_ap_N; JNK_SAPK-associated protein-1
      pfam16471
      Location:446 → 514
      JIP_LZII; JNK-interacting protein leucine zipper II
      cl23720
      Location:461 → 574
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

    12. XM_005224532.4 → XP_005224589.1  C-Jun-amino-terminal kinase-interacting protein 3 isoform X11

      UniProtKB/TrEMBL
      A0A3Q1MTK3, A0A8J8XE10, E1BN82, M5FMW2
      Related
      ENSBTAP00000002865.7, ENSBTAT00000002865.7
      Conserved Domains (5) summary
      pfam05887
      Location:849 → 968
      Trypan_PARP; Procyclic acidic repetitive protein (PARP)
      pfam05103
      Location:38 → 167
      DivIVA; DivIVA protein
      pfam09744
      Location:30 → 183
      Jnk-SapK_ap_N; JNK_SAPK-associated protein-1
      pfam16471
      Location:416 → 484
      JIP_LZII; JNK-interacting protein leucine zipper II
      cl23720
      Location:431 → 544
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

    13. XM_005224537.5 → XP_005224594.1  C-Jun-amino-terminal kinase-interacting protein 3 isoform X16

      UniProtKB/TrEMBL
      A0A3Q1LQI8, A0A8J8Y2F9, M5FKI5
      Conserved Domains (4) summary
      pfam05887
      Location:834 → 953
      Trypan_PARP; Procyclic acidic repetitive protein (PARP)
      pfam05103
      Location:38 → 167
      DivIVA; DivIVA protein
      pfam09744
      Location:30 → 183
      Jnk-SapK_ap_N; JNK_SAPK-associated protein-1
      pfam16471
      Location:410 → 478
      JIP_LZII; JNK-interacting protein leucine zipper II

    14. XM_010819119.3 → XP_010817421.1  C-Jun-amino-terminal kinase-interacting protein 3 isoform X13

      UniProtKB/TrEMBL
      A0A3Q1MTK3, A0A8J8XE10, M5FMW2
      Conserved Domains (5) summary
      pfam05887
      Location:848 → 967
      Trypan_PARP; Procyclic acidic repetitive protein (PARP)
      pfam05103
      Location:38 → 167
      DivIVA; DivIVA protein
      pfam09744
      Location:30 → 183
      Jnk-SapK_ap_N; JNK_SAPK-associated protein-1
      pfam16471
      Location:415 → 483
      JIP_LZII; JNK-interacting protein leucine zipper II
      cl23720
      Location:430 → 543
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

    15. XM_010819122.3 → XP_010817424.1  C-Jun-amino-terminal kinase-interacting protein 3 isoform X18

      UniProtKB/TrEMBL
      A0A3Q1MTK3, A0A8J8XE10, M5FMW2
      Conserved Domains (5) summary
      pfam05887
      Location:818 → 937
      Trypan_PARP; Procyclic acidic repetitive protein (PARP)
      pfam05103
      Location:38 → 167
      DivIVA; DivIVA protein
      pfam09744
      Location:30 → 183
      Jnk-SapK_ap_N; JNK_SAPK-associated protein-1
      pfam16471
      Location:385 → 453
      JIP_LZII; JNK-interacting protein leucine zipper II
      cl23720
      Location:400 → 513
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

    16. XM_010819124.3 → XP_010817426.1  C-Jun-amino-terminal kinase-interacting protein 3 isoform X20

      UniProtKB/TrEMBL
      A0A3Q1LQI8, A0A8J8Y2F9, M5FKI5
      Conserved Domains (5) summary
      pfam05887
      Location:812 → 931
      Trypan_PARP; Procyclic acidic repetitive protein (PARP)
      pfam05103
      Location:38 → 167
      DivIVA; DivIVA protein
      pfam09744
      Location:30 → 183
      Jnk-SapK_ap_N; JNK_SAPK-associated protein-1
      pfam16471
      Location:379 → 447
      JIP_LZII; JNK-interacting protein leucine zipper II
      cl23720
      Location:394 → 507
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

    17. XM_010819113.3 → XP_010817415.1  C-Jun-amino-terminal kinase-interacting protein 3 isoform X6

      UniProtKB/TrEMBL
      A0A3Q1MTK3, A0A8J8XE10, M5FMW2
      Conserved Domains (5) summary
      pfam05887
      Location:878 → 997
      Trypan_PARP; Procyclic acidic repetitive protein (PARP)
      pfam05103
      Location:38 → 167
      DivIVA; DivIVA protein
      pfam09744
      Location:30 → 183
      Jnk-SapK_ap_N; JNK_SAPK-associated protein-1
      pfam16471
      Location:445 → 513
      JIP_LZII; JNK-interacting protein leucine zipper II
      cl23720
      Location:460 → 573
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

    18. XM_005224533.4 → XP_005224590.1  C-Jun-amino-terminal kinase-interacting protein 3 isoform X12

      See identical proteins and their annotated locations for XP_005224590.1

      UniProtKB/TrEMBL
      A0A3Q1MTK3, A0A8J8XE10, M5FMW2
      Conserved Domains (5) summary
      pfam05887
      Location:848 → 967
      Trypan_PARP; Procyclic acidic repetitive protein (PARP)
      pfam05103
      Location:38 → 167
      DivIVA; DivIVA protein
      pfam09744
      Location:30 → 183
      Jnk-SapK_ap_N; JNK_SAPK-associated protein-1
      pfam16471
      Location:415 → 483
      JIP_LZII; JNK-interacting protein leucine zipper II
      cl23720
      Location:430 → 543
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

    19. XM_010819120.3 → XP_010817422.1  C-Jun-amino-terminal kinase-interacting protein 3 isoform X15

      UniProtKB/TrEMBL
      A0A3Q1MTK3, A0A8J8XE10, M5FMW2
      Conserved Domains (5) summary
      pfam05887
      Location:847 → 966
      Trypan_PARP; Procyclic acidic repetitive protein (PARP)
      pfam05103
      Location:38 → 167
      DivIVA; DivIVA protein
      pfam09744
      Location:30 → 183
      Jnk-SapK_ap_N; JNK_SAPK-associated protein-1
      pfam16471
      Location:414 → 482
      JIP_LZII; JNK-interacting protein leucine zipper II
      cl23720
      Location:429 → 542
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

    20. XM_010819123.3 → XP_010817425.1  C-Jun-amino-terminal kinase-interacting protein 3 isoform X19

      UniProtKB/TrEMBL
      A0A3Q1MTK3, A0A8J8XE10, M5FMW2
      Conserved Domains (5) summary
      pfam05887
      Location:817 → 936
      Trypan_PARP; Procyclic acidic repetitive protein (PARP)
      pfam05103
      Location:38 → 167
      DivIVA; DivIVA protein
      pfam09744
      Location:30 → 183
      Jnk-SapK_ap_N; JNK_SAPK-associated protein-1
      pfam16471
      Location:384 → 452
      JIP_LZII; JNK-interacting protein leucine zipper II
      cl23720
      Location:399 → 512
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

    21. XM_010819125.4 → XP_010817427.1  C-Jun-amino-terminal kinase-interacting protein 3 isoform X21

      UniProtKB/TrEMBL
      A0A3Q1MTK3, A0A8J8XE10, M5FMW2
      Conserved Domains (3) summary
      pfam05887
      Location:625 → 744
      Trypan_PARP; Procyclic acidic repetitive protein (PARP)
      pfam04871
      Location:202 → 325
      Uso1_p115_C; Uso1 / p115 like vesicle tethering protein, C terminal region
      pfam16471
      Location:192 → 260
      JIP_LZII; JNK-interacting protein leucine zipper II
    Nucleotide Protein Strain
    Heading Accession and Version

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