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    Xlr X-linked lymphocyte-regulated [ Mus musculus (house mouse) ]

    Gene ID: 22441, updated on 9-Dec-2024

    Summary

    Official Symbol
    Xlrprovided by MGI
    Official Full Name
    X-linked lymphocyte-regulatedprovided by MGI
    Primary source
    MGI:MGI:98976
    See related
    Ensembl:ENSMUSG00000054626 AllianceGenome:MGI:98976
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to be involved in meiotic cell cycle and spermatid development. Predicted to be active in synaptonemal complex. Is expressed in gonad and thymus. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in placenta adult (RPKM 1.3), liver E14 (RPKM 0.3) and 10 other tissues See more
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    Genomic context

    See Xlr in Genome Data Viewer
    Location:
    X A5; X 30.06 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (52779084..52799673, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (53777118..53797716, complement)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene predicted pseudogene 6025 Neighboring gene zinc finger protein 36, C3H type-like 3 Neighboring gene 60S ribosomal protein L37 pseudogene Neighboring gene X-linked lymphocyte-regulated complex pseudogene Neighboring gene predicted gene, 38663

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in meiotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in spermatid development IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in synaptonemal complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    X-linked lymphocyte-regulated protein PM1
    Names
    X-linked gene family of B-cell surface antigens
    X-linked lymphocyte-regulated complex

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001291747.2NP_001278676.1  X-linked lymphocyte-regulated protein PM1 isoform a

      See identical proteins and their annotated locations for NP_001278676.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2, and 4-8 all encode the same isoform (a).
      Source sequence(s)
      AL691513
      Consensus CDS
      CCDS30139.1
      UniProtKB/Swiss-Prot
      P05531
      UniProtKB/TrEMBL
      Q544L6
      Related
      ENSMUSP00000110458.2, ENSMUST00000114810.2
      Conserved Domains (1) summary
      pfam04803
      Location:61192
      Cor1; Cor1/Xlr/Xmr conserved region
    2. NM_001291748.1NP_001278677.1  X-linked lymphocyte-regulated protein PM1 isoform b

      See identical proteins and their annotated locations for NP_001278677.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR, the 3' UTR, and the 3' coding sequence compared to variant 1. The resulting isoform (b) has a shorter and distinct C-terminus compared to isoform a. Variants 3, 9, and 10 all encode the same isoform (b).
      Source sequence(s)
      AK035025, AL691513
      Consensus CDS
      CCDS81127.1
      UniProtKB/TrEMBL
      Q8BS74
      Related
      ENSMUSP00000066162.2, ENSMUST00000067782.8
      Conserved Domains (1) summary
      pfam04803
      Location:63162
      Cor1; Cor1/Xlr/Xmr conserved region
    3. NM_001426070.1NP_001412999.1  X-linked lymphocyte-regulated protein PM1 isoform a

      Status: VALIDATED

      Source sequence(s)
      AL691513
      UniProtKB/Swiss-Prot
      P05531
      UniProtKB/TrEMBL
      Q544L6
    4. NM_001426071.1NP_001413000.1  X-linked lymphocyte-regulated protein PM1 isoform a

      Status: VALIDATED

      Source sequence(s)
      AL691513
      UniProtKB/Swiss-Prot
      P05531
      UniProtKB/TrEMBL
      Q544L6
    5. NM_001426072.1NP_001413001.1  X-linked lymphocyte-regulated protein PM1 isoform a

      Status: VALIDATED

      Source sequence(s)
      AL691513
      UniProtKB/Swiss-Prot
      P05531
      UniProtKB/TrEMBL
      Q544L6
    6. NM_001426073.1NP_001413002.1  X-linked lymphocyte-regulated protein PM1 isoform a

      Status: VALIDATED

      Source sequence(s)
      AL691513
      UniProtKB/Swiss-Prot
      P05531
      UniProtKB/TrEMBL
      Q544L6
    7. NM_001426074.1NP_001413003.1  X-linked lymphocyte-regulated protein PM1 isoform a

      Status: VALIDATED

      Source sequence(s)
      AL691513
      UniProtKB/Swiss-Prot
      P05531
      UniProtKB/TrEMBL
      Q544L6
    8. NM_001426075.1NP_001413004.1  X-linked lymphocyte-regulated protein PM1 isoform b

      Status: VALIDATED

      Source sequence(s)
      AL691513
      UniProtKB/TrEMBL
      Q8BS74
    9. NM_001426076.1NP_001413005.1  X-linked lymphocyte-regulated protein PM1 isoform b

      Status: VALIDATED

      Source sequence(s)
      AL691513
      UniProtKB/TrEMBL
      Q8BS74
    10. NM_011725.5NP_035855.1  X-linked lymphocyte-regulated protein PM1 isoform a

      See identical proteins and their annotated locations for NP_035855.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longer isoform (a). Variants 1, 2, and 4-8 all encode the same isoform (a).
      Source sequence(s)
      AL691513
      Consensus CDS
      CCDS30139.1
      UniProtKB/Swiss-Prot
      P05531
      UniProtKB/TrEMBL
      Q544L6
      Related
      ENSMUSP00000068044.4, ENSMUST00000067763.10
      Conserved Domains (1) summary
      pfam04803
      Location:61192
      Cor1; Cor1/Xlr/Xmr conserved region

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      52779084..52799673 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)