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    Zfp799 zinc finger protein 799 [ Mus musculus (house mouse) ]

    Gene ID: 240064, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Zfp799provided by MGI
    Official Full Name
    zinc finger protein 799provided by MGI
    Primary source
    MGI:MGI:2443934
    See related
    Ensembl:ENSMUSG00000095253 AllianceGenome:MGI:2443934
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    6030490I01Rik
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in diencephalon floor plate; early conceptus; inner cell mass; limb mesenchyme; and midbrain floor plate. Orthologous to several human genes including ZNF700 (zinc finger protein 700) and ZNF878 (zinc finger protein 878). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in whole brain E14.5 (RPKM 4.0), CNS E11.5 (RPKM 3.5) and 27 other tissues See more
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    Genomic context

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    See Zfp799 in Genome Data Viewer
    Location:
    17 B1; 17 17.98 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (33031125..33049235, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (32815449..32830261, complement)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer mm9_chr17:32925111-32925412 Neighboring gene predicted gene 17115 Neighboring gene zinc finger protein 811 Neighboring gene predicted gene, 23294 Neighboring gene zinc finger protein 458 pseudogene Neighboring gene predicted gene 7059

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Guo G, et al. Dev Cell, 2010 Apr 20. PMID 20412781
    2. A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Yokoyama S, et al. Dev Cell, 2009 Dec. PMID 20059953, Free PMC Article
    3. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
    4. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
    5. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 799

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001293229.1 → NP_001280158.1  zinc finger protein 799 isoform 2

      See identical proteins and their annotated locations for NP_001280158.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate 3'-terminal exon, which extends past a splice site that is used in variant 3. The encoded isoform (2) has a shorter and distinct C-terminus.
      Source sequence(s)
      BC062813, CT485613
      Consensus CDS
      CCDS79529.1
      UniProtKB/TrEMBL
      A0A0J9YUA4, A0A0J9YUH8, Q6P5N6
      Related
      ENSMUSP00000143907.2, ENSMUST00000201499.2
      Conserved Domains (1) summary
      pfam01352
      Location:4 → 40
      KRAB; KRAB box

    2. NM_001360479.1 → NP_001347408.1  zinc finger protein 799 isoform 3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) encodes the longest isoform (3).
      Source sequence(s)
      CT485613
      Conserved Domains (3) summary
      COG5048
      Location:251 → 638
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:227 → 247
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:3 → 44
      KRAB; KRAB box

    3. NM_177359.5 → NP_796333.3  zinc finger protein 799 isoform 1

      See identical proteins and their annotated locations for NP_796333.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) uses an alternate in-frame splice site in the 3' coding region, compared to variant 3. It encodes isoform 1 which is shorter, compared to isoform 3z.
      Source sequence(s)
      AK031686, BC096552, BM933667, CT485613
      Consensus CDS
      CCDS79530.1
      UniProtKB/TrEMBL
      Q8BHK4
      Related
      ENSMUSP00000144480.2, ENSMUST00000202988.4
      Conserved Domains (4) summary
      COG5048
      Location:145 → 548
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:225 → 245
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:4 → 40
      KRAB; KRAB box
      pfam13465
      Location:237 → 262
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      33031125..33049235 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011246442.4 → XP_011244744.1  zinc finger protein 799 isoform X2

      Conserved Domains (3) summary
      COG5048
      Location:248 → 635
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:224 → 244
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:3 → 44
      KRAB; KRAB box

    2. XM_011246441.4 → XP_011244743.1  zinc finger protein 799 isoform X1

      Conserved Domains (3) summary
      COG5048
      Location:250 → 637
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:226 → 246
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:3 → 44
      KRAB; KRAB box
    Nucleotide Protein Strain
    Heading Accession and Version

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