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    Zfp317 zinc finger protein 317 [ Mus musculus (house mouse) ]

    Gene ID: 244713, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Zfp317provided by MGI
    Official Full Name
    zinc finger protein 317provided by MGI
    Primary source
    MGI:MGI:107775
    See related
    Ensembl:ENSMUSG00000057551 AllianceGenome:MGI:107775
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    KRAB9; Zfp67; Zfp75; mszf40; 4932416G03; D230022C05Rik
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZNF317 (zinc finger protein 317). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in CNS E18 (RPKM 4.1), CNS E11.5 (RPKM 4.0) and 26 other tissues See more
    Orthologs
    human all
    NEW
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    Genomic context

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    See Zfp317 in Genome Data Viewer
    Location:
    9 A3; 9 7.35 cM
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (19533315..19561039)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (19622038..19649743)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_23440 Neighboring gene olfactory receptor family 7 subfamily G member 34 Neighboring gene olfactory receptor family 7 subfamily G member 35 Neighboring gene STARR-positive B cell enhancer ABC_E3816 Neighboring gene CapStarr-seq enhancer MGSCv37_chr9:19426670-19426779 Neighboring gene olfactory receptor family 7 subfamily D member 12, pseudogene 1 Neighboring gene STARR-seq mESC enhancer starr_23442 Neighboring gene BCL2/adenovirus E1B interacting protein 2 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Deletion of ARGLU1 causes global defects in alternative splicing in vivo and mouse cortical malformations primarily via apoptosis. Yao F, et al. Cell Death Dis, 2023 Aug 23. PMID 37612280, Free PMC Article
    2. Emergence of the ZNF91 Krüppel-associated box-containing zinc finger gene family in the last common ancestor of anthropoidea. Bellefroid EJ, et al. Proc Natl Acad Sci U S A, 1995 Nov 7. PMID 7479878, Free PMC Article
    3. Activation of the c-H-ras proto-oncogene by retrovirus insertion and chromosomal rearrangement in a Moloney leukemia virus-induced T-cell leukemia. Ihle JN, et al. J Virol, 1989 Jul. PMID 2542606, Free PMC Article
    4. Rapid and efficient cloning of cDNAs encoding Krüppel-like zinc finger proteins by degenerate PCR. Agata Y, et al. Gene, 1998 Jun 15. PMID 9630514
    5. Chromosomal location of fifteen unique mouse KRAB-containing zinc finger loci. Marine JC, et al. Mamm Genome, 1996 Jun. PMID 8662221

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 317
    Names
    zinc finger protein 75

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_172918.4 → NP_766506.4  zinc finger protein 317

      See identical proteins and their annotated locations for NP_766506.4

      Status: VALIDATED

      Source sequence(s)
      AC132277, AK045365, AK051946, BC059211
      Consensus CDS
      CCDS22862.1
      UniProtKB/TrEMBL
      Q8C0Q5
      Related
      ENSMUSP00000146876.2, ENSMUST00000208694.2
      Conserved Domains (3) summary
      smart00349
      Location:60 → 118
      KRAB; krueppel associated box
      COG5048
      Location:223 → 570
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:505 → 525
      ZF_C2H2; C2H2 Zn finger [structural motif]

    RNA

    1. NR_153375.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC132277, BC059211

    2. NR_153376.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC132277, BC059211

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      19533315..19561039
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006510277.5 → XP_006510340.1  zinc finger protein 317 isoform X1

      See identical proteins and their annotated locations for XP_006510340.1

      UniProtKB/TrEMBL
      Q8C0Q5
      Conserved Domains (3) summary
      smart00349
      Location:60 → 118
      KRAB; krueppel associated box
      COG5048
      Location:223 → 570
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:505 → 525
      ZF_C2H2; C2H2 Zn finger [structural motif]

    2. XM_030244356.2 → XP_030100216.1  zinc finger protein 317 isoform X1

      UniProtKB/TrEMBL
      Q8C0Q5
      Conserved Domains (3) summary
      smart00349
      Location:60 → 118
      KRAB; krueppel associated box
      COG5048
      Location:223 → 570
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:505 → 525
      ZF_C2H2; C2H2 Zn finger [structural motif]

    3. XM_036154977.1 → XP_036010870.1  zinc finger protein 317 isoform X5

      Conserved Domains (2) summary
      COG5048
      Location:10 → 357
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:292 → 312
      ZF_C2H2; C2H2 Zn finger [structural motif]

    4. XM_006510282.5 → XP_006510345.1  zinc finger protein 317 isoform X1

      See identical proteins and their annotated locations for XP_006510345.1

      UniProtKB/TrEMBL
      Q8C0Q5
      Conserved Domains (3) summary
      smart00349
      Location:60 → 118
      KRAB; krueppel associated box
      COG5048
      Location:223 → 570
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:505 → 525
      ZF_C2H2; C2H2 Zn finger [structural motif]

    5. XM_030244359.2 → XP_030100219.1  zinc finger protein 317 isoform X5

      Conserved Domains (2) summary
      COG5048
      Location:10 → 357
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:292 → 312
      ZF_C2H2; C2H2 Zn finger [structural motif]

    6. XM_006510283.5 → XP_006510346.1  zinc finger protein 317 isoform X1

      See identical proteins and their annotated locations for XP_006510346.1

      UniProtKB/TrEMBL
      Q8C0Q5
      Conserved Domains (3) summary
      smart00349
      Location:60 → 118
      KRAB; krueppel associated box
      COG5048
      Location:223 → 570
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:505 → 525
      ZF_C2H2; C2H2 Zn finger [structural motif]

    7. XM_006510289.4 → XP_006510352.1  zinc finger protein 317 isoform X2

      See identical proteins and their annotated locations for XP_006510352.1

      Conserved Domains (3) summary
      smart00349
      Location:52 → 110
      KRAB; krueppel associated box
      COG5048
      Location:215 → 562
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:497 → 517
      ZF_C2H2; C2H2 Zn finger [structural motif]

    8. XM_006510285.5 → XP_006510348.1  zinc finger protein 317 isoform X1

      See identical proteins and their annotated locations for XP_006510348.1

      UniProtKB/TrEMBL
      Q8C0Q5
      Conserved Domains (3) summary
      smart00349
      Location:60 → 118
      KRAB; krueppel associated box
      COG5048
      Location:223 → 570
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:505 → 525
      ZF_C2H2; C2H2 Zn finger [structural motif]

    9. XM_030244358.2 → XP_030100218.1  zinc finger protein 317 isoform X5

      Conserved Domains (2) summary
      COG5048
      Location:10 → 357
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:292 → 312
      ZF_C2H2; C2H2 Zn finger [structural motif]

    10. XM_006510288.4 → XP_006510351.1  zinc finger protein 317 isoform X2

      See identical proteins and their annotated locations for XP_006510351.1

      Conserved Domains (3) summary
      smart00349
      Location:52 → 110
      KRAB; krueppel associated box
      COG5048
      Location:215 → 562
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:497 → 517
      ZF_C2H2; C2H2 Zn finger [structural motif]

    11. XM_036154979.1 → XP_036010872.1  zinc finger protein 317 isoform X5

      Conserved Domains (2) summary
      COG5048
      Location:10 → 357
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:292 → 312
      ZF_C2H2; C2H2 Zn finger [structural motif]

    12. XM_036154972.1 → XP_036010865.1  zinc finger protein 317 isoform X3

      Related
      ENSMUSP00000151161.2, ENSMUST00000213725.2
      Conserved Domains (3) summary
      COG5048
      Location:135 → 482
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:417 → 437
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02581
      Location:1 → 30
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

    13. XM_006510284.5 → XP_006510347.1  zinc finger protein 317 isoform X1

      See identical proteins and their annotated locations for XP_006510347.1

      UniProtKB/TrEMBL
      Q8C0Q5
      Related
      ENSMUSP00000078051.7, ENSMUST00000079042.7
      Conserved Domains (3) summary
      smart00349
      Location:60 → 118
      KRAB; krueppel associated box
      COG5048
      Location:223 → 570
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:505 → 525
      ZF_C2H2; C2H2 Zn finger [structural motif]

    14. XM_036154975.1 → XP_036010868.1  zinc finger protein 317 isoform X4

      Conserved Domains (2) summary
      COG5048
      Location:102 → 449
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:384 → 404
      ZF_C2H2; C2H2 Zn finger [structural motif]

    15. XM_036154974.1 → XP_036010867.1  zinc finger protein 317 isoform X3

      Conserved Domains (3) summary
      COG5048
      Location:135 → 482
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:417 → 437
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02581
      Location:1 → 30
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

    16. XM_036154969.1 → XP_036010862.1  zinc finger protein 317 isoform X1

      UniProtKB/TrEMBL
      Q8C0Q5
      Conserved Domains (3) summary
      smart00349
      Location:60 → 118
      KRAB; krueppel associated box
      COG5048
      Location:223 → 570
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:505 → 525
      ZF_C2H2; C2H2 Zn finger [structural motif]

    17. XM_017313365.2 → XP_017168854.1  zinc finger protein 317 isoform X1

      UniProtKB/TrEMBL
      Q8C0Q5
      Conserved Domains (3) summary
      smart00349
      Location:60 → 118
      KRAB; krueppel associated box
      COG5048
      Location:223 → 570
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:505 → 525
      ZF_C2H2; C2H2 Zn finger [structural motif]

    18. XM_017313366.2 → XP_017168855.1  zinc finger protein 317 isoform X1

      UniProtKB/TrEMBL
      Q8C0Q5
      Conserved Domains (3) summary
      smart00349
      Location:60 → 118
      KRAB; krueppel associated box
      COG5048
      Location:223 → 570
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:505 → 525
      ZF_C2H2; C2H2 Zn finger [structural motif]

    19. XM_017313369.2 → XP_017168858.1  zinc finger protein 317 isoform X2

      Conserved Domains (3) summary
      smart00349
      Location:52 → 110
      KRAB; krueppel associated box
      COG5048
      Location:215 → 562
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:497 → 517
      ZF_C2H2; C2H2 Zn finger [structural motif]

    20. XM_011242518.3 → XP_011240820.1  zinc finger protein 317 isoform X2

      See identical proteins and their annotated locations for XP_011240820.1

      Conserved Domains (3) summary
      smart00349
      Location:52 → 110
      KRAB; krueppel associated box
      COG5048
      Location:215 → 562
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:497 → 517
      ZF_C2H2; C2H2 Zn finger [structural motif]

    21. XM_036154973.1 → XP_036010866.1  zinc finger protein 317 isoform X3

      Conserved Domains (3) summary
      COG5048
      Location:135 → 482
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:417 → 437
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02581
      Location:1 → 30
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

    22. XM_011242517.3 → XP_011240819.1  zinc finger protein 317 isoform X1

      See identical proteins and their annotated locations for XP_011240819.1

      UniProtKB/TrEMBL
      Q8C0Q5
      Conserved Domains (3) summary
      smart00349
      Location:60 → 118
      KRAB; krueppel associated box
      COG5048
      Location:223 → 570
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:505 → 525
      ZF_C2H2; C2H2 Zn finger [structural motif]

    23. XM_036154978.1 → XP_036010871.1  zinc finger protein 317 isoform X5

      Conserved Domains (2) summary
      COG5048
      Location:10 → 357
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:292 → 312
      ZF_C2H2; C2H2 Zn finger [structural motif]

    24. XM_030244361.1 → XP_030100221.1  zinc finger protein 317 isoform X5

      Conserved Domains (2) summary
      COG5048
      Location:10 → 357
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:292 → 312
      ZF_C2H2; C2H2 Zn finger [structural motif]

    25. XM_036154976.1 → XP_036010869.1  zinc finger protein 317 isoform X5

      Conserved Domains (2) summary
      COG5048
      Location:10 → 357
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:292 → 312
      ZF_C2H2; C2H2 Zn finger [structural motif]

    26. XM_011242515.3 → XP_011240817.1  zinc finger protein 317 isoform X1

      See identical proteins and their annotated locations for XP_011240817.1

      UniProtKB/TrEMBL
      Q8C0Q5
      Conserved Domains (3) summary
      smart00349
      Location:60 → 118
      KRAB; krueppel associated box
      COG5048
      Location:223 → 570
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:505 → 525
      ZF_C2H2; C2H2 Zn finger [structural motif]

    27. XM_017313368.2 → XP_017168857.1  zinc finger protein 317 isoform X2

      Conserved Domains (3) summary
      smart00349
      Location:52 → 110
      KRAB; krueppel associated box
      COG5048
      Location:215 → 562
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:497 → 517
      ZF_C2H2; C2H2 Zn finger [structural motif]

    28. XM_017313372.2 → XP_017168861.1  zinc finger protein 317 isoform X5

      Conserved Domains (2) summary
      COG5048
      Location:10 → 357
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:292 → 312
      ZF_C2H2; C2H2 Zn finger [structural motif]

    29. XM_011242514.3 → XP_011240816.1  zinc finger protein 317 isoform X1

      See identical proteins and their annotated locations for XP_011240816.1

      UniProtKB/TrEMBL
      Q8C0Q5
      Conserved Domains (3) summary
      smart00349
      Location:60 → 118
      KRAB; krueppel associated box
      COG5048
      Location:223 → 570
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:505 → 525
      ZF_C2H2; C2H2 Zn finger [structural motif]

    30. XM_017313367.2 → XP_017168856.1  zinc finger protein 317 isoform X2

      Conserved Domains (3) summary
      smart00349
      Location:52 → 110
      KRAB; krueppel associated box
      COG5048
      Location:215 → 562
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:497 → 517
      ZF_C2H2; C2H2 Zn finger [structural motif]

    31. XM_036154980.1 → XP_036010873.1  zinc finger protein 317 isoform X5

      Conserved Domains (2) summary
      COG5048
      Location:10 → 357
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:292 → 312
      ZF_C2H2; C2H2 Zn finger [structural motif]

    32. XM_030244357.1 → XP_030100217.1  zinc finger protein 317 isoform X1

      UniProtKB/TrEMBL
      Q8C0Q5
      Conserved Domains (3) summary
      smart00349
      Location:60 → 118
      KRAB; krueppel associated box
      COG5048
      Location:223 → 570
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:505 → 525
      ZF_C2H2; C2H2 Zn finger [structural motif]

    33. XM_006510280.4 → XP_006510343.1  zinc finger protein 317 isoform X1

      See identical proteins and their annotated locations for XP_006510343.1

      UniProtKB/TrEMBL
      Q8C0Q5
      Conserved Domains (3) summary
      smart00349
      Location:60 → 118
      KRAB; krueppel associated box
      COG5048
      Location:223 → 570
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:505 → 525
      ZF_C2H2; C2H2 Zn finger [structural motif]

    34. XM_030244360.1 → XP_030100220.1  zinc finger protein 317 isoform X5

      Conserved Domains (2) summary
      COG5048
      Location:10 → 357
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:292 → 312
      ZF_C2H2; C2H2 Zn finger [structural motif]

    35. XM_036154970.1 → XP_036010863.1  zinc finger protein 317 isoform X1

      UniProtKB/TrEMBL
      Q8C0Q5
      Conserved Domains (3) summary
      smart00349
      Location:60 → 118
      KRAB; krueppel associated box
      COG5048
      Location:223 → 570
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:505 → 525
      ZF_C2H2; C2H2 Zn finger [structural motif]

    36. XM_036154971.1 → XP_036010864.1  zinc finger protein 317 isoform X1

      UniProtKB/TrEMBL
      Q8C0Q5
      Related
      ENSMUSP00000150705.2, ENSMUST00000215372.2
      Conserved Domains (3) summary
      smart00349
      Location:60 → 118
      KRAB; krueppel associated box
      COG5048
      Location:223 → 570
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:505 → 525
      ZF_C2H2; C2H2 Zn finger [structural motif]
    Nucleotide Protein Strain
    Heading Accession and Version

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