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    Ighv1-12 immunoglobulin heavy variable V1-12 [ Mus musculus (house mouse) ]

    Gene ID: 629860, updated on 2-Nov-2024

    Summary

    Official Symbol
    Ighv1-12provided by MGI
    Official Full Name
    immunoglobulin heavy variable V1-12provided by MGI
    Primary source
    MGI:MGI:3646284
    See related
    Ensembl:ENSMUSG00000095416 IMGT/GENE-DB:IGHV1-12; AllianceGenome:MGI:3646284
    Gene type
    other
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm7011; EG629860
    Summary
    Predicted to enable antigen binding activity. Predicted to be involved in immunoglobulin mediated immune response. Orthologous to human IGHV1-24 (immunoglobulin heavy variable 1-24); IGHV1-45 (immunoglobulin heavy variable 1-45); and IGHV1-69-2 (immunoglobulin heavy variable 1-69-2). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

    See Ighv1-12 in Genome Data Viewer
    Location:
    12 F2; 12 62.41 cM
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (114579470..114579763, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (114615850..114616143, complement)

    Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene immunoglobulin heavy chain complex Neighboring gene CapStarr-seq enhancer MGSCv37_chr12:115847540-115847723 Neighboring gene immunoglobulin heavy variable V1-10 Neighboring gene immunoglobulin heavy variable V1-11 Neighboring gene immunoglobulin heavy variable V1-13 Neighboring gene immunoglobulin heavy variable 1-14

    Genomic regions, transcripts, and products

    General gene information

    Other Names

    • anti-human CD20 antibody 1F5 gamma heavy chain variable region

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables antigen binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in immunoglobulin mediated immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_005838.1 

      Range
      1368254..1368547 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      114579470..114579763 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)