Snrnp25 small nuclear ribonucleoprotein U11/U12 subunit 25 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Snrnp25provided by RGD
Official Full Name: small nuclear ribonucleoprotein U11/U12 subunit 25provided by RGD
Primary source: RGD:1310922
See related: AllianceGenome:RGD:1310922
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1310922
Summary: Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in cytosol; intercellular bridge; and nucleoplasm. Predicted to be part of U12-type spliceosomal complex. Orthologous to human SNRNP25 (small nuclear ribonucleoprotein U11/U12 subunit 25). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Liver (RPKM 280.4), Thymus (RPKM 110.6) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 10q12

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	10	NC_086028.1 (15924932..15928279, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	10	NC_051345.1 (15420482..15423806, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	10	NC_005109.4 (15685999..15689338, complement)

Chromosome 10 - NC_086028.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

3300001G02Rik (e-PCR), detects polymorphism
- UniSTS:508356

Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in mRNA splicing, via spliceosome	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of U12-type spliceosomal complex	IBA Inferred from Biological aspect of Ancestor more info
part_of U12-type spliceosomal complex	ISO Inferred from Sequence Orthology more info
located_in cytosol	ISO Inferred from Sequence Orthology more info
located_in intercellular bridge	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
located_in nucleus	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: U11/U12 small nuclear ribonucleoprotein 25 kDa protein

Names: minus -99 protein; small nuclear ribonucleoprotein 25 (U11/U12)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001398566.1 → NP_001385495.1 U11/U12 small nuclear ribonucleoprotein 25 kDa protein

Status: VALIDATED

Source sequence(s)

JAXUCZ010000010

UniProtKB/TrEMBL

A6HDB5, D3ZE11

Conserved Domains (1) summary

cd17058
Location:31 → 119

Ubl_SNRNP25; ubiquitin-like (Ubl) domain found in small nuclear ribonucleoprotein U11/U12 subunit 25 (SNRNP25) and similar proteins