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    Slc35b3 solute carrier family 35 member B3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 306866, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Slc35b3provided by RGD
    Official Full Name
    solute carrier family 35 member B3provided by RGD
    Primary source
    RGD:1307183
    See related
    EnsemblRapid:ENSRNOG00000016174 AllianceGenome:RGD:1307183
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity. Predicted to be involved in 3'-phosphoadenosine 5'-phosphosulfate transport and transmembrane transport. Predicted to be active in Golgi membrane and endoplasmic reticulum membrane. Orthologous to human SLC35B3 (solute carrier family 35 member B3). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 106.4), Spleen (RPKM 100.3) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Slc35b3 in Genome Data Viewer
    Location:
    17p12
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (26052249..26078686)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (25846590..25873115)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (26478777..26505225)

    Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene N-terminal Xaa-Pro-Lys N-methyltransferase 1, pseudogene 1 Neighboring gene uncharacterized LOC120097954 Neighboring gene protein regulator of cytokinesis 1, pseudogene 1 Neighboring gene DNA polymerase epsilon 3, accessory subunit, pseudogene 2 Neighboring gene eukaryotic translation elongation factor 1 epsilon 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Mootha VK, et al. Cell, 2003 Nov 26. PMID 14651853
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in 3'-phospho-5'-adenylyl sulfate transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in 3'-phosphoadenosine 5'-phosphosulfate transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in 5'-adenylyl sulfate transmembrane transport ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in peptidyl-tyrosine sulfation ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in Golgi membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in trans-Golgi network ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    adenosine 3'-phospho 5'-phosphosulfate transporter 2
    Names
    solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107346.1 → NP_001100816.1  adenosine 3'-phospho 5'-phosphosulfate transporter 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000017
      UniProtKB/TrEMBL
      A0A8I6ACP7, A6J795
      Related
      ENSRNOP00000089959.1, ENSRNOT00000112405.2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086035.1 Reference GRCr8

      Range
      26052249..26078686
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006253853.5 → XP_006253915.1  adenosine 3'-phospho 5'-phosphosulfate transporter 2 isoform X4

      See identical proteins and their annotated locations for XP_006253915.1

      Conserved Domains (1) summary
      pfam08449
      Location:90 → 341
      UAA; UAA transporter family

    2. XM_006253854.5 → XP_006253916.1  adenosine 3'-phospho 5'-phosphosulfate transporter 2 isoform X5

      See identical proteins and their annotated locations for XP_006253916.1

      Conserved Domains (1) summary
      pfam08449
      Location:90 → 340
      UAA; UAA transporter family

    3. XM_039096462.2 → XP_038952390.1  adenosine 3'-phospho 5'-phosphosulfate transporter 2 isoform X3

      Conserved Domains (1) summary
      pfam08449
      Location:90 → 367
      UAA; UAA transporter family

    4. XM_225253.11 → XP_225253.5  adenosine 3'-phospho 5'-phosphosulfate transporter 2 isoform X1

      See identical proteins and their annotated locations for XP_225253.5

      UniProtKB/TrEMBL
      D4AAG3
      Related
      ENSRNOP00000021670.4, ENSRNOT00000021669.8
      Conserved Domains (1) summary
      pfam08449
      Location:90 → 381
      UAA; UAA transporter family

    5. XM_039096465.2 → XP_038952393.1  adenosine 3'-phospho 5'-phosphosulfate transporter 2 isoform X8

      Conserved Domains (1) summary
      pfam08449
      Location:90 → 240
      UAA; UAA transporter family

    6. XM_039096464.2 → XP_038952392.1  adenosine 3'-phospho 5'-phosphosulfate transporter 2 isoform X8

      Conserved Domains (1) summary
      pfam08449
      Location:90 → 240
      UAA; UAA transporter family

    7. XM_039096466.2 → XP_038952394.1  adenosine 3'-phospho 5'-phosphosulfate transporter 2 isoform X8

      Conserved Domains (1) summary
      pfam08449
      Location:90 → 240
      UAA; UAA transporter family

    8. XM_006253852.5 → XP_006253914.1  adenosine 3'-phospho 5'-phosphosulfate transporter 2 isoform X3

      See identical proteins and their annotated locations for XP_006253914.1

      Conserved Domains (1) summary
      pfam08449
      Location:90 → 367
      UAA; UAA transporter family

    9. XM_039096463.2 → XP_038952391.1  adenosine 3'-phospho 5'-phosphosulfate transporter 2 isoform X7

      Conserved Domains (1) summary
      pfam08449
      Location:90 → 301
      UAA; UAA transporter family

    10. XM_039096467.2 → XP_038952395.1  adenosine 3'-phospho 5'-phosphosulfate transporter 2 isoform X9

      Conserved Domains (1) summary
      pfam08449
      Location:90 → 240
      UAA; UAA transporter family

    11. XM_039096468.2 → XP_038952396.1  adenosine 3'-phospho 5'-phosphosulfate transporter 2 isoform X10

      Conserved Domains (1) summary
      pfam08449
      Location:48 → 259
      UAA; UAA transporter family

    12. XM_063276389.1 → XP_063132459.1  adenosine 3'-phospho 5'-phosphosulfate transporter 2 isoform X12

    13. XM_063276387.1 → XP_063132457.1  adenosine 3'-phospho 5'-phosphosulfate transporter 2 isoform X6

      UniProtKB/TrEMBL
      A6J797

    14. XM_006253856.4 → XP_006253918.1  adenosine 3'-phospho 5'-phosphosulfate transporter 2 isoform X2

      See identical proteins and their annotated locations for XP_006253918.1

      UniProtKB/TrEMBL
      A0A8I6ACP7, A6J795
      Conserved Domains (1) summary
      pfam08449
      Location:48 → 339
      UAA; UAA transporter family

    15. XM_063276388.1 → XP_063132458.1  adenosine 3'-phospho 5'-phosphosulfate transporter 2 isoform X10

    16. XM_006253850.3 → XP_006253912.1  adenosine 3'-phospho 5'-phosphosulfate transporter 2 isoform X2

      See identical proteins and their annotated locations for XP_006253912.1

      UniProtKB/TrEMBL
      A0A8I6ACP7, A6J795
      Conserved Domains (1) summary
      pfam08449
      Location:48 → 339
      UAA; UAA transporter family

    17. XM_006253855.5 → XP_006253917.1  adenosine 3'-phospho 5'-phosphosulfate transporter 2 isoform X2

      See identical proteins and their annotated locations for XP_006253917.1

      UniProtKB/TrEMBL
      A0A8I6ACP7, A6J795
      Conserved Domains (1) summary
      pfam08449
      Location:48 → 339
      UAA; UAA transporter family

    18. XM_039096469.1 → XP_038952397.1  adenosine 3'-phospho 5'-phosphosulfate transporter 2 isoform X11

      Conserved Domains (1) summary
      pfam08449
      Location:1 → 225
      UAA; UAA transporter family

    19. XM_039096470.1 → XP_038952398.1  adenosine 3'-phospho 5'-phosphosulfate transporter 2 isoform X13

      Conserved Domains (1) summary
      pfam08449
      Location:1 → 166
      UAA; UAA transporter family

    20. XM_039096471.1 → XP_038952399.1  adenosine 3'-phospho 5'-phosphosulfate transporter 2 isoform X13

      Conserved Domains (1) summary
      pfam08449
      Location:1 → 166
      UAA; UAA transporter family

    RNA

    1. XR_010058863.1 RNA Sequence

    2. XR_005495896.2 RNA Sequence

    3. XR_010058864.1 RNA Sequence

    4. XR_005495897.2 RNA Sequence

    5. XR_005495898.2 RNA Sequence

    6. XR_005495901.2 RNA Sequence

    7. XR_010058865.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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