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    Mall mal, T-cell differentiation protein-like [ Rattus norvegicus (Norway rat) ]

    Gene ID: 362211, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Mallprovided by RGD
    Official Full Name
    mal, T-cell differentiation protein-likeprovided by RGD
    Primary source
    RGD:1310869
    See related
    EnsemblRapid:ENSRNOG00000015599 AllianceGenome:RGD:1310869
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1310869
    Summary
    Predicted to be a structural constituent of myelin sheath. Predicted to be involved in myelination. Predicted to be located in several cellular components, including Golgi membrane; clathrin-coated vesicle; and membrane raft. Predicted to be active in membrane. Orthologous to human MALL (mal, T cell differentiation protein like). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 29.2), Muscle (RPKM 20.6) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Mall in Genome Data Viewer
    Location:
    3q36
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (135381180..135404136, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (114927897..114950840, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (120272583..120307090, complement)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134486436 Neighboring gene uncharacterized LOC102555822 Neighboring gene nephrocystin 1 Neighboring gene WW domain containing adaptor with coiled-coil, pseudogene 2 Neighboring gene mitoregulin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. BENE, a novel raft-associated protein of the MAL proteolipid family, interacts with caveolin-1 in human endothelial-like ECV304 cells. de Marco MC, et al. J Biol Chem, 2001 Jun 22. PMID 11294831
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC95101

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in Golgi membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in clathrin-coated vesicle ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytoplasmic vesicle ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in membrane raft ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    MAL-like protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014182.1 → NP_001014204.1  MAL-like protein

      See identical proteins and their annotated locations for NP_001014204.1

      Status: PROVISIONAL

      Source sequence(s)
      BC090079
      UniProtKB/TrEMBL
      A6HQ26, F7FDK2, Q5EB48
      Related
      ENSRNOP00000021082.4, ENSRNOT00000021082.7
      Conserved Domains (1) summary
      pfam01284
      Location:25 → 149
      MARVEL; Membrane-associating domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      135381180..135404136 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008762181.4 → XP_008760403.1  MAL-like protein isoform X1

      Conserved Domains (1) summary
      pfam01284
      Location:25 → 115
      MARVEL; Membrane-associating domain

    RNA

    1. XR_352582.5 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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