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    ab BTB/POZ-zinc finger protein abrupt [ Tribolium castaneum (red flour beetle) ]

    Gene ID: 663820, updated on 9-Oct-2024

    Summary

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    Gene symbol
    ab
    Gene description
    BTB/POZ-zinc finger protein abrupt
    Locus tag
    TcasGA2_TC033240
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Tribolium castaneum
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia; Tenebrionidae; Tenebrionidae incertae sedis; Tribolium
    Orthologs
    fruit fly all
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    Genomic context

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    Location:
    chromosome: 5
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_04 current icTriCast1.1 (GCF_031307605.1) 5 NC_087398.1 (1792388..1817647)
    103 previous assembly Tcas5.2 (GCF_000002335.3) Linkage Group LG5 NC_007420.3 (13901571..13926737, complement)

    Chromosome 5 - NC_087398.1Genomic Context describing neighboring genes Neighboring gene Na[+]/H[+] hydrogen antiporter 1 Neighboring gene Calcium channel protein beta subunit Neighboring gene uncharacterized LOC107397994 Neighboring gene cuticle protein CP14.6 Neighboring gene focal adhesion protein tensin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The BTB transcription factor, Abrupt, acts cooperatively with Chronologically inappropriate morphogenesis (Chinmo) to repress metamorphosis and promotes leg regeneration. Khong H, et al. Dev Biol, 2024 May. PMID 38373692
    2. Comparative developmental analysis of Drosophila and Tribolium reveals conserved and diverged roles of abrupt in insect wing evolution. Ravisankar P, et al. Dev Biol, 2016 Jan 15. PMID 26687509
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The BTB transcription factor, Abrupt, acts cooperatively with Chronologically inappropriate morphogenesis (Chinmo) to repress metamorphosis and promotes leg regeneration.
      Title: The BTB transcription factor, Abrupt, acts cooperatively with Chronologically inappropriate morphogenesis (Chinmo) to repress metamorphosis and promotes leg regeneration.
    2. ab is essential for proper wing vein patterning both in Tribolium and Drosophila.
      Title: Comparative developmental analysis of Drosophila and Tribolium reveals conserved and diverged roles of abrupt in insect wing evolution.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein abrupt
    Names
    AUGUSTUS-3.0.2_33240
    Protein abrupt-like Protein
    abrupt

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_031307605.1-RS_2024_04

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference icTriCast1.1 Primary Assembly

    Genomic

    1. NC_087398.1 Reference icTriCast1.1 Primary Assembly

      Range
      1792388..1817647
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008196168.3 → XP_008194390.1  protein abrupt isoform X1

      See identical proteins and their annotated locations for XP_008194390.1

      UniProtKB/TrEMBL
      A0A139WHP2
      Conserved Domains (5) summary
      PHA02664
      Location:114 → 239
      PHA02664; hypothetical protein; Provisional
      smart00225
      Location:37 → 122
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00020
      Location:320 → 341
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00651
      Location:26 → 122
      BTB; BTB/POZ domain
      pfam12756
      Location:320 → 377
      zf-C2H2_2; C2H2 type zinc-finger (2 copies)

    2. XM_008196167.3 → XP_008194389.1  protein abrupt isoform X1

      See identical proteins and their annotated locations for XP_008194389.1

      UniProtKB/TrEMBL
      A0A139WHP2
      Conserved Domains (5) summary
      PHA02664
      Location:114 → 239
      PHA02664; hypothetical protein; Provisional
      smart00225
      Location:37 → 122
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00020
      Location:320 → 341
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00651
      Location:26 → 122
      BTB; BTB/POZ domain
      pfam12756
      Location:320 → 377
      zf-C2H2_2; C2H2 type zinc-finger (2 copies)

    3. XM_008196166.3 → XP_008194388.1  protein abrupt isoform X1

      See identical proteins and their annotated locations for XP_008194388.1

      UniProtKB/TrEMBL
      A0A139WHP2
      Conserved Domains (5) summary
      PHA02664
      Location:114 → 239
      PHA02664; hypothetical protein; Provisional
      smart00225
      Location:37 → 122
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00020
      Location:320 → 341
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00651
      Location:26 → 122
      BTB; BTB/POZ domain
      pfam12756
      Location:320 → 377
      zf-C2H2_2; C2H2 type zinc-finger (2 copies)

    4. XM_008196169.3 → XP_008194391.1  protein abrupt isoform X2

      Conserved Domains (5) summary
      PHA02664
      Location:114 → 239
      PHA02664; hypothetical protein; Provisional
      smart00225
      Location:37 → 122
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00020
      Location:320 → 341
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00651
      Location:26 → 122
      BTB; BTB/POZ domain
      pfam12756
      Location:320 → 377
      zf-C2H2_2; C2H2 type zinc-finger (2 copies)

    5. XM_969854.5 → XP_974947.2  protein abrupt isoform X1

      See identical proteins and their annotated locations for XP_974947.2

      UniProtKB/TrEMBL
      A0A139WHP2
      Conserved Domains (5) summary
      PHA02664
      Location:114 → 239
      PHA02664; hypothetical protein; Provisional
      smart00225
      Location:37 → 122
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00020
      Location:320 → 341
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00651
      Location:26 → 122
      BTB; BTB/POZ domain
      pfam12756
      Location:320 → 377
      zf-C2H2_2; C2H2 type zinc-finger (2 copies)
    Nucleotide Protein Strain
    Heading Accession and Version

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