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    Clip4 CAP-GLY domain containing linker protein family, member 4 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 298801, updated on 9-Dec-2024

    Summary

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    Symbol
    Clip4provided by RGD
    Full Name
    CAP-GLY domain containing linker protein family, member 4provided by RGD
    Primary source
    RGD:1311049
    See related
    EnsemblRapid:ENSRNOG00000008806 AllianceGenome:RGD:1311049
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Rsnl2; RGD1311049
    Summary
    Predicted to be located in intracellular membrane-bounded organelle. Orthologous to human CLIP4 (CAP-Gly domain containing linker protein family member 4). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 542.2), Muscle (RPKM 310.9) and 2 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Clip4 in Genome Data Viewer
    Location:
    6q14
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (29359628..29449365, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (23616280..23697625, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (23222020..23316962, complement)

    Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108351183 Neighboring gene ALK receptor tyrosine kinase Neighboring gene stratifin like 1 Neighboring gene uncharacterized LOC108351180 Neighboring gene histidine-rich glycoprotein-like Neighboring gene TOG array regulator of axonemal microtubules 2 Neighboring gene photoreceptor cilium actin regulator

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in intracellular membrane-bounded organelle IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    CAP-Gly domain-containing linker protein 4
    Names
    restin-like 2
    restin-like protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013942.2 → NP_001013964.1  CAP-Gly domain-containing linker protein 4 isoform 2

      See identical proteins and their annotated locations for NP_001013964.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000006
      UniProtKB/Swiss-Prot
      Q66HD5
      UniProtKB/TrEMBL
      A0A0G2K6G4
      Related
      ENSRNOP00000073802.3, ENSRNOT00000085708.3
      Conserved Domains (4) summary
      cd00204
      Location:98 → 252
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam01302
      Location:488 → 551
      CAP_GLY; CAP-Gly domain
      pfam12796
      Location:111 → 217
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:153 → 184
      ANK; ANK repeat [structural motif]

    2. NM_001428603.1 → NP_001415532.1  CAP-Gly domain-containing linker protein 4 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000006

    3. NM_001428604.1 → NP_001415533.1  CAP-Gly domain-containing linker protein 4 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000006

    4. NM_001428605.1 → NP_001415534.1  CAP-Gly domain-containing linker protein 4 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000006

    5. NM_001428606.1 → NP_001415535.1  CAP-Gly domain-containing linker protein 4 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000006

    6. NM_001428607.1 → NP_001415536.1  CAP-Gly domain-containing linker protein 4 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000006

    7. NM_001428608.1 → NP_001415537.1  CAP-Gly domain-containing linker protein 4 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000006
      UniProtKB/Swiss-Prot
      Q66HD5
      UniProtKB/TrEMBL
      A0A0G2K6G4

    8. NM_001428609.1 → NP_001415538.1  CAP-Gly domain-containing linker protein 4 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000006
      UniProtKB/Swiss-Prot
      Q66HD5
      UniProtKB/TrEMBL
      A0A0G2K6G4

    9. NM_001428610.1 → NP_001415539.1  CAP-Gly domain-containing linker protein 4 isoform 3

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000006

    RNA

    1. NR_190422.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000006

    2. NR_190423.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000006

    3. NR_190424.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000006

    4. NR_190425.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000006

    5. NR_190426.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000006

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086024.1 Reference GRCr8

      Range
      29359628..29449365 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    2. NC_086024.1 Reference GRCr8

      Range
      29349245..29351890 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063261626.1 → XP_063117696.1  CAP-Gly domain-containing linker protein 4 isoform X1

      Related
      ENSRNOP00000111998.1, ENSRNOT00000144084.1

    2. XM_063261628.1 → XP_063117698.1  CAP-Gly domain-containing linker protein 4 isoform X1

    3. XM_063261627.1 → XP_063117697.1  CAP-Gly domain-containing linker protein 4 isoform X1

    RNA

    1. XR_010052058.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q66HD5.1 GenPept UniProtKB/Swiss-Prot:Q66HD5

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