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    toe2 protein toe2 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541956, updated on 14-Nov-2024

    Summary

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    Official Symbol
    toe2
    Official Full Name
    protein toe2
    Primary source
    PomBase:SPAC139.03
    Locus tag
    SPOM_SPAC139.03
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See toe2 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    3
    Sequence:
    Chromosome: I; NC_003424.3 (1021670..1024135)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene post-transcriptional RNA stability regulator Mkt1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene anion transporter Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene L-saccharopine oxidase Neighboring gene ncRNA Neighboring gene succinate-semialdehyde dehydrogenase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional characterization of fission yeast transcription factors by overexpression analysis. Vachon L, et al. Genetics, 2013 Aug. PMID 23695302, Free PMC Article
    2. Promoter nucleosome dynamics regulated by signalling through the CTD code. Materne P, et al. Elife, 2015 Jun 22. PMID 26098123, Free PMC Article
    3. Predicting the fission yeast protein interaction network. Pancaldi V, et al. G3 (Bethesda), 2012 Apr. PMID 22540037, Free PMC Article
    4. A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human. Vo TV, et al. Cell, 2016 Jan 14. PMID 26771498, Free PMC Article
    5. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables DNA-binding transcription activator activity, RNA polymerase II-specific IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding ISM
    Inferred from Sequence Model
    more info
    		  
    enables zinc ion binding ISM
    Inferred from Sequence Model
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of pyrimidine-containing compound salvage IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in chromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in mitotic spindle HDA PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    protein toe2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      1021670..1024135
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001018567.3 → NP_593170.1  protein toe2 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593170.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9UTN0
      Conserved Domains (2) summary
      cd12148
      Location:186 → 581
      fungal_TF_MHR; fungal transcription factor regulatory middle homology region
      smart00066
      Location:17 → 56
      GAL4; GAL4-like Zn(II)2Cys6 (or C6 zinc) binuclear cluster DNA-binding domain
    Nucleotide Protein
    Heading Accession and Version

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