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    Zswim9 zinc finger SWIM-type containing 9 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 308381, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Zswim9provided by RGD
    Official Full Name
    zinc finger SWIM-type containing 9provided by RGD
    Primary source
    RGD:1310257
    See related
    EnsemblRapid:ENSRNOG00000014186 AllianceGenome:RGD:1310257
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1310257
    Summary
    Predicted to enable zinc ion binding activity. Predicted to act upstream of or within hematopoietic progenitor cell differentiation. Orthologous to human ZSWIM9 (zinc finger SWIM-type containing 9). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 19.4), Thymus (RPKM 17.6) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Zswim9 in Genome Data Viewer
    Location:
    1q21
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (83222133..83243116, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (74144818..74165804, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (75335183..75356130, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene vomeronasal 1 receptor 61 Neighboring gene uncharacterized LOC134485101 Neighboring gene vomeronasal 1 receptor 62 Neighboring gene DNA ligase 1 Neighboring gene phospholipase A2 group IVC Neighboring gene pellino 1, pseudogene 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7. Nagamachi A, et al. Cancer Cell, 2013 Sep 9. PMID 24029230

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within hematopoietic progenitor cell differentiation ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC308381; uncharacterized protein ZSWIM9
    Names
    uncharacterized protein C19orf68 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001432222.1 → NP_001419151.1  uncharacterized protein LOC308381 isoform a

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A0A8I5ZUL5

    2. NM_001432223.1 → NP_001419152.1  uncharacterized protein LOC308381 isoform a

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A0A8I5ZUL5

    3. NM_001432224.1 → NP_001419153.1  uncharacterized protein LOC308381 isoform a

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A0A8I5ZUL5

    4. NM_001432225.1 → NP_001419154.1  uncharacterized protein LOC308381 isoform a

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A0A8I5ZUL5

    5. NM_001432226.1 → NP_001419155.1  uncharacterized protein LOC308381 isoform b

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001

    6. NM_001432227.1 → NP_001419156.1  uncharacterized protein LOC308381 isoform b

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      83222133..83243116 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006228322.3 → XP_006228384.1  uncharacterized protein ZSWIM9 isoform X1

      See identical proteins and their annotated locations for XP_006228384.1

      UniProtKB/TrEMBL
      D3ZHE3
      Conserved Domains (1) summary
      cl00458
      Location:787 → 877
      Peptidase_A8; Signal peptidase (SPase) II

    2. XM_006228323.4 → XP_006228385.1  uncharacterized protein ZSWIM9 isoform X2

      Conserved Domains (1) summary
      cl00458
      Location:755 → 845
      Peptidase_A8; Signal peptidase (SPase) II

    3. XM_006228324.4 → XP_006228386.1  uncharacterized protein ZSWIM9 isoform X2

      Related
      ENSRNOP00000018989.7, ENSRNOT00000018989.8
      Conserved Domains (1) summary
      cl00458
      Location:755 → 845
      Peptidase_A8; Signal peptidase (SPase) II

    4. XM_006228325.4 → XP_006228387.1  uncharacterized protein ZSWIM9 isoform X2

      Conserved Domains (1) summary
      cl00458
      Location:755 → 845
      Peptidase_A8; Signal peptidase (SPase) II

    5. XM_017589984.3 → XP_017445473.1  uncharacterized protein ZSWIM9 isoform X2

      UniProtKB/TrEMBL
      A0A8I5ZUL5

    6. XM_039100811.1 → XP_038956739.1  uncharacterized protein ZSWIM9 isoform X3

      UniProtKB/TrEMBL
      A6KSL8
      Conserved Domains (1) summary
      pfam17738
      Location:1 → 114
      DUF5575; Family of unknown function (DUF5575)

    7. XM_039100810.2 → XP_038956738.1  uncharacterized protein ZSWIM9 isoform X3

      UniProtKB/TrEMBL
      A6KSL8
      Conserved Domains (1) summary
      pfam17738
      Location:1 → 114
      DUF5575; Family of unknown function (DUF5575)
    Nucleotide Protein Strain
    Heading Accession and Version

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