stam signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 [Haplochromis burtoni (Burton's mouthbrooder)] - Gene

Summary

Gene symbol: stam
Gene description: signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
See related: Ensembl:ENSHBUG00000000342
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Haplochromis burtoni
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids; Pseudocrenilabrinae; Haplochromini; Haplochromis
Orthologs: zebrafish all
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Genomic context

Location:: chromosome: Un

Exon count:: 24

Annotation release	Status	Assembly	Chr	Location
102	current	NCSU_Asbu1 (GCF_018398535.1)	Unplaced Scaffold	NW_024582364.1 (6828722..6873482)
101	previous assembly	AstBur1.0 (GCF_000239415.1)	Unplaced Scaffold	NW_005179402.1 (196819..208801, complement)

NW_024582364.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables phosphatidylinositol binding	IEA Inferred from Electronic Annotation more info	PubMed
enables signaling receptor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables ubiquitin binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of ESCRT-0 complex	IEA Inferred from Electronic Annotation more info	PubMed
located_in collagen-containing extracellular matrix	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: collectin-12; signal transducing adaptor molecule (SH3 domain and ITAM motif) 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001433716.1 → NP_001420645.1 signal transducing adaptor molecule (SH3 domain and ITAM motif) 1

Status: VALIDATED

Source sequence(s)

JAGKPV010000003

UniProtKB/TrEMBL

A0A3Q2X0U4

RefSeqs of Annotated Genomes: Haplochromis burtoni Annotation Release 102 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NCSU_Asbu1 Primary Assembly

Genomic

NW_024582364.1 Reference NCSU_Asbu1 Primary Assembly

Range

6828722..6873482

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005912432.2 → XP_005912494.1 collectin-12 isoform X1

Related

ENSHBUP00000028449.1

Conserved Domains (7) summary

cd03590
Location:626 → 752

CLECT_DC-SIGN_like; C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR)

pfam01391
Location:456 → 527

Collagen; Collagen triple helix repeat (20 copies)

COG3352
Location:294 → 420

FlaC; Archaellum component FlaC [Cell motility]

pfam07926
Location:174 → 295

TPR_MLP1_2; TPR/MLP1/MLP2-like protein

pfam16043
Location:208 → 329

DUF4795; Domain of unknown function (DUF4795)

cl02488
Location:103 → 267

SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...

cl23720
Location:166 → 246

RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)
XM_005912431.3 → XP_005912493.2 collectin-12 isoform X2

Conserved Domains (5) summary

cd03590
Location:626 → 747

CLECT_DC-SIGN_like; C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR)

cd11964
Location:962 → 1016

SH3_STAM1; Src homology 3 domain of Signal Transducing Adaptor Molecule 1

COG1196
Location:55 → 420

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

PRK12323
Location:1132 → 1267

PRK12323; DNA polymerase III subunit gamma/tau

cd17000
Location:757 → 887

VHS_STAM1; VHS (Vps27/Hrs/STAM) domain of Signal Transducing Adapter Molecule 1