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    POFUT2 protein O-fucosyltransferase 2 [ Sus scrofa (pig) ]

    Gene ID: 100738385, updated on 21-Dec-2024

    Summary

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    Official Symbol
    POFUT2provided by VGNC
    Official Full Name
    protein O-fucosyltransferase 2provided by VGNC
    Primary source
    VGNC:VGNC:91621
    See related
    Ensembl:ENSSSCG00000012088
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Expression
    Ubiquitous expression in ovary (RPKM 23.5), subcutaneous adipose (RPKM 13.5) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See POFUT2 in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 13 NC_010455.5 (207801101..207818138, complement)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 13 NC_010455.4 (217902861..217919990)

    Chromosome 13 - NC_010455.5Genomic Context describing neighboring genes Neighboring gene serine/threonine-protein kinase WNK4-like Neighboring gene adenosine deaminase RNA specific B1 Neighboring gene collagen type XVIII alpha 1 chain Neighboring gene solute carrier family 19 member 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Bibliography

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    Related articles in PubMed

    1. PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Uenishi H, et al. Nucleic Acids Res, 2007 Jan. PMID 17145712, Free PMC Article
    2. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables peptide-O-fucosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein O-linked fucosylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    GDP-fucose protein O-fucosyltransferase 2; protein O-fucosyltransferase 2
    XP_020927184.1
    XP_020927185.1
    XP_020927186.1
    XP_020927187.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001435321.1 → NP_001422250.1  protein O-fucosyltransferase 2 precursor

      Status: VALIDATED

      Source sequence(s)
      AEMK02000094

    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010455.5 Reference Sscrofa11.1 Primary Assembly

      Range
      207801101..207818138 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021071525.1 → XP_020927184.1  GDP-fucose protein O-fucosyltransferase 2 isoform X1

      UniProtKB/TrEMBL
      A0A8D1Q0U5, F1SG35
      Related
      ENSSSCP00000012870.5, ENSSSCT00000013222.5
      Conserved Domains (2) summary
      cd11298
      Location:45 → 379
      O-FucT-2; GDP-fucose protein O-fucosyltransferase 2
      cl26464
      Location:389 → 591
      Atrophin-1; Atrophin-1 family

    2. XM_021071526.1 → XP_020927185.1  GDP-fucose protein O-fucosyltransferase 2 isoform X2

      Conserved Domains (2) summary
      cl16914
      Location:1 → 164
      O-FucT_like; GDP-fucose protein O-fucosyltransferase and related proteins
      cl26464
      Location:174 → 376
      Atrophin-1; Atrophin-1 family

    3. XM_021071527.1 → XP_020927186.1  GDP-fucose protein O-fucosyltransferase 2 isoform X2

      Conserved Domains (2) summary
      cl16914
      Location:1 → 164
      O-FucT_like; GDP-fucose protein O-fucosyltransferase and related proteins
      cl26464
      Location:174 → 376
      Atrophin-1; Atrophin-1 family

    4. XM_021071528.1 → XP_020927187.1  GDP-fucose protein O-fucosyltransferase 2 isoform X3

      UniProtKB/TrEMBL
      A0A480W777, A0A4X1T886, A0A5G2RAY2
      Related
      ENSSSCP00000074162.1, ENSSSCT00000082740.2
      Conserved Domains (1) summary
      cd11298
      Location:45 → 414
      O-FucT-2; GDP-fucose protein O-fucosyltransferase 2
    Nucleotide Protein
    Heading Accession and Version

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