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    PBP4 Pbp4p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851507, updated on 9-Dec-2024

    Summary

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    Official Symbol
    PBP4
    Official Full Name
    Pbp4p
    Primary source
    SGD:S000002211
    Locus tag
    YDL053C
    See related
    AllianceGenome:SGD:S000002211; FungiDB:YDL053C; VEuPathDB:YDL053C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Located in cytoplasmic stress granule and peroxisome. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See PBP4 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (361699..362256, complement)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene tRNA-Lys Neighboring gene Mch1p Neighboring gene 1-acylglycerol-3-phosphate O-acyltransferase SLC1 Neighboring gene Lhp1p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001136.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of factors regulating poly(A) tail synthesis and maturation. Mangus DA, et al. Mol Cell Biol, 2004 May. PMID 15121841, Free PMC Article
    2. Localization to, and effects of Pbp1, Pbp4, Lsm12, Dhh1, and Pab1 on stress granules in Saccharomyces cerevisiae. Swisher KD, et al. PLoS One, 2010 Apr 2. PMID 20368989, Free PMC Article
    3. Processing body and stress granule assembly occur by independent and differentially regulated pathways in Saccharomyces cerevisiae. Shah KH, et al. Genetics, 2013 Jan. PMID 23105015, Free PMC Article
    4. Roles for Pbp1 and caloric restriction in genome and lifespan maintenance via suppression of RNA-DNA hybrids. Salvi JS, et al. Dev Cell, 2014 Jul 28. PMID 25073155
    5. Identification of the novel TRAPP associated protein Tca17. Montpetit B, et al. Traffic, 2009 Jun. PMID 19220810

    See all (69) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Pbp4 and Lsm12 proteins did not dramatically affect the formation of stress granules or P-bodies.
      Title: Localization to, and effects of Pbp1, Pbp4, Lsm12, Dhh1, and Pab1 on stress granules in Saccharomyces cerevisiae.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasmic stress granule HDA PubMed 
    located_in cytoplasmic stress granule IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus HDA PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in peroxisome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Pbp4p
    NP_010230.1
    • Pbp1p binding protein; interacts strongly with Pab1p-binding protein 1 (Pbp1p) in the yeast two-hybrid system; also interacts with Lsm12p in a copurification assay; relative distribution to the nucleus increases upon DNA replication stress; also detected in peroxisomes

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      361699..362256 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180112.1 → NP_010230.1  TPA: Pbp4p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010230.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VRU3, Q07362
      UniProtKB/TrEMBL
      A6ZXS2, B3LGV1, C8Z4L6, N1P631
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q07362.1

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