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    COX23 Cox23p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856516, updated on 9-Dec-2024

    Summary

    Official Symbol
    COX23
    Official Full Name
    Cox23p
    Primary source
    SGD:S000001158
    Locus tag
    YHR116W
    See related
    AllianceGenome:SGD:S000001158; FungiDB:YHR116W; VEuPathDB:YHR116W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in mitochondrial respiratory chain complex assembly. Located in mitochondrion. Orthologous to human CHCHD7 (coiled-coil-helix-coiled-coil-helix domain containing 7). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See COX23 in Genome Data Viewer
    Location:
    chromosome: VIII
    Exon count:
    1
    Sequence:
    Chromosome: VIII; NC_001140.6 (341665..342120)

    Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene Bzz1p Neighboring gene ubiquitin-conjugating protein DMA1 Neighboring gene protein channel TOM71 Neighboring gene origin recognition complex subunit 6

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in mitochondrial respiratory chain complex assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in mitochondrial respiratory chain complex assembly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrial intermembrane space IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Cox23p
    NP_011984.1
    • Protein that functions in mitochondrial copper homeostasis; mitochondrial intermembrane space protein; essential for functional cytochrome oxidase expression; homologous to Cox17p; contains twin cysteine-x9-cysteine motifs

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001140.6 Reference assembly

      Range
      341665..342120
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179246.1NP_011984.1  TPA: Cox23p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011984.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D3DL66, P38824
      UniProtKB/TrEMBL
      A6ZT24, B3LSN1, C7GR62, C8Z9Q9, N1P4N8
      Conserved Domains (1) summary
      pfam06747
      Location:104138
      CHCH; CHCH domain