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    SPS100 Sps100p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856541, updated on 9-Dec-2024

    Summary

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    Official Symbol
    SPS100
    Official Full Name
    Sps100p
    Primary source
    SGD:S000001181
    Locus tag
    YHR139C
    See related
    AllianceGenome:SGD:S000001181; FungiDB:YHR139C; VEuPathDB:YHR139C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in ascospore wall assembly. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See SPS100 in Genome Data Viewer
    Location:
    chromosome: VIII
    Exon count:
    1
    Sequence:
    Chromosome: VIII; NC_001140.6 (378219..379199, complement)

    Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene aromatic-amino-acid:2-oxoglutarate transaminase Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001140.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Upregulation of SPS100 gene expression by an antisense RNA via a switch of mRNA isoforms with different stabilities. Bunina D, et al. Nucleic Acids Res, 2017 Nov 2. PMID 28977638, Free PMC Article
    2. The SPS100 gene of Saccharomyces cerevisiae is activated late in the sporulation process and contributes to spore wall maturation. Law DT, et al. Mol Cell Biol, 1988 Feb. PMID 3280971, Free PMC Article
    3. Increased copy number of the 5' end of the SPS2 gene inhibits sporulation of Saccharomyces cerevisiae. Percival-Smith A, et al. Mol Cell Biol, 1987 Jul. PMID 3302678, Free PMC Article
    4. Mechanisms of patulin toxicity under conditions that inhibit yeast growth. Iwahashi Y, et al. J Agric Food Chem, 2006 Mar 8. PMID 16506856
    5. Annotating novel genes by integrating synthetic lethals and genomic information. Schöner D, et al. BMC Syst Biol, 2008 Jan 14. PMID 18194531, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Results indicate a role for the antisense RNA (asRNAs) on the regulation of the abundance of different SPS100 mRNA isoforms.
      Title: Upregulation of SPS100 gene expression by an antisense RNA via a switch of mRNA isoforms with different stabilities.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in ascospore wall assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in sporulation resulting in formation of a cellular spore IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    Sps100p
    NP_012007.1
    • Protein required for spore wall maturation; expressed during sporulation; may be a component of the spore wall; expression also induced in cells treated with the mycotoxin patulin; SPS100 has a paralog, YGP1, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001140.6 Reference assembly

      Range
      378219..379199 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179269.1 → NP_012007.1  TPA: Sps100p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012007.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D3DL88, P13130
      UniProtKB/TrEMBL
      B3LSQ3, C7GTW6, C8Z9T5, G2WFL2, N1P4R5
      Conserved Domains (1) summary
      cl00216
      Location:33 → 318
      L-asparaginase_like; Bacterial L-asparaginases and related enzymes
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P13130.1

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