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    ADY4 Ady4p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 850924, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ADY4
    Official Full Name
    Ady4p
    Primary source
    SGD:S000004217
    Locus tag
    YLR227C
    See related
    AllianceGenome:SGD:S000004217; FungiDB:YLR227C; VEuPathDB:YLR227C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables structural molecule activity. Involved in ascospore formation. Located in meiotic spindle pole body. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ADY4 in Genome Data Viewer
    Location:
    chromosome: XII
    Exon count:
    1
    Sequence:
    Chromosome: XII; NC_001144.5 (590562..592043, complement)

    Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Bur2p Neighboring gene tRNA-Leu Neighboring gene gag protein Neighboring gene gag-pol fusion protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001144.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Recruitment of the lipid kinase Mss4 to the meiotic spindle pole promotes prospore membrane formation in Saccharomyces cerevisiae. Nunez G, et al. Mol Biol Cell, 2023 Apr 1. PMID 36857169, Free PMC Article
    2. Membrane assembly modulates the stability of the meiotic spindle-pole body. Mathieson EM, et al. J Cell Sci, 2010 Jul 15. PMID 20592185, Free PMC Article
    3. Ady4p and Spo74p are components of the meiotic spindle pole body that promote growth of the prospore membrane in Saccharomyces cerevisiae. Nickas ME, et al. Eukaryot Cell, 2003 Jun. PMID 12796288, Free PMC Article
    4. A screen for genes required for meiosis and spore formation based on whole-genome expression. Rabitsch KP, et al. Curr Biol, 2001 Jul 10. PMID 11470404
    5. An overexpression screen in Saccharomyces cerevisiae identifies novel genes that affect endocytic protein trafficking. Arlt H, et al. Traffic, 2011 Nov. PMID 21777356

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables structural molecule activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural molecule activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in ascospore formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in cell division IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in meiotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in sporulation resulting in formation of a cellular spore IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in meiotic spindle pole body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in meiotic spindle pole body IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    located_in spindle pole body IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Ady4p
    NP_013328.1
    • Structural component of the meiotic outer plaque; outer plaque is a membrane-organizing center that assembles on the cytoplasmic face of the spindle pole body during meiosis II and triggers the formation of the prospore membrane

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001144.5 Reference assembly

      Range
      590562..592043 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182114.1 → NP_013328.1  TPA: Ady4p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013328.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VYM7, Q05955
      UniProtKB/TrEMBL
      C8ZDJ1, N1P6W5
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q05955.1

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