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    CIS1 Cis1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851060, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CIS1
    Official Full Name
    Cis1p
    Primary source
    SGD:S000004338
    Locus tag
    YLR346C
    See related
    AllianceGenome:SGD:S000004338; FungiDB:YLR346C; VEuPathDB:YLR346C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Located in mitochondrion. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See CIS1 in Genome Data Viewer
    Location:
    chromosome: XII
    Exon count:
    1
    Sequence:
    Chromosome: XII; NC_001144.5 (822287..822592, complement)

    Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene ribosomal 60S subunit protein L26A Neighboring gene bifunctional fructose-2,6-bisphosphate 2-phosphatase/6-phosphofructo-2-kinase Neighboring gene karyopherin beta Neighboring gene Dic1p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001144.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Dissecting the Genetic Basis of a Complex cis-Regulatory Adaptation. Naranjo S, et al. PLoS Genet, 2015 Dec. PMID 26713447, Free PMC Article
    2. Development of a yeast biosensor-biocatalyst for the detection and biodegradation of the organophosphate paraoxon. Schofield DA, et al. Appl Microbiol Biotechnol, 2007 Oct. PMID 17665192
    3. Novel target genes of the yeast regulator Pdr1p: a contribution of the TPO1 gene in resistance to quinidine and other drugs. do Valle Matta MA, et al. Gene, 2001 Jul 11. PMID 11470516
    4. New insights into the pleiotropic drug resistance network from genome-wide characterization of the YRR1 transcription factor regulation system. Le Crom S, et al. Mol Cell Biol, 2002 Apr. PMID 11909958, Free PMC Article
    5. MitoCPR-A surveillance pathway that protects mitochondria in response to protein import stress. Weidberg H, et al. Science, 2018 Apr 13. PMID 29650645, Free PMC Article

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Cis1p
    NP_013450.1
    • hypothetical protein found in mitochondria; expression is regulated by transcription factors involved in pleiotropic drug resistance, Pdr1p and Yrr1p; not an essential gene; YLR346C has a paralog, YGR035C, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001144.5 Reference assembly

      Range
      822287..822592 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182235.1 → NP_013450.1  TPA: Cis1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013450.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VYY5, Q06139
      UniProtKB/TrEMBL
      A7A1M5, B3RHL6, C7GRX2, C8ZDV3, G2WJG5, N1P772
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q06139.1

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