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    DML1 Dml1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855251, updated on 9-Dec-2024

    Summary

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    Official Symbol
    DML1
    Official Full Name
    Dml1p
    Primary source
    SGD:S000004824
    Locus tag
    YMR211W
    See related
    AllianceGenome:SGD:S000004824; FungiDB:YMR211W; VEuPathDB:YMR211W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in mitochondrial genome maintenance and plasmid maintenance. Located in mitochondrion. Orthologous to human MSTO1 (misato mitochondrial distribution and morphology regulator 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See DML1 in Genome Data Viewer
    Location:
    chromosome: XIII
    Exon count:
    1
    Sequence:
    Chromosome: XIII; NC_001145.3 (689083..690510)

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene putative carboxylic ester hydrolase Neighboring gene Efr3p Neighboring gene Cef1p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001145.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Preliminary characterisation of DML1, an essential Saccharomyces cerevisiae gene related to misato of Drosophila melanogaster. Gurvitz A, et al. FEMS Yeast Res, 2002 May. PMID 12702300
    2. Host factors that affect Ty3 retrotransposition in Saccharomyces cerevisiae. Aye M, et al. Genetics, 2004 Nov. PMID 15579677, Free PMC Article
    3. Btn3 regulates the endosomal sorting function of the yeast Ent3 epsin, an adaptor for SNARE proteins. Morvan J, et al. J Cell Sci, 2015 Feb 15. PMID 25512335
    4. Dosage suppression genetic interaction networks enhance functional wiring diagrams of the cell. Magtanong L, et al. Nat Biotechnol, 2011 May 15. PMID 21572441, Free PMC Article
    5. Heterozygous screen in Saccharomyces cerevisiae identifies dosage-sensitive genes that affect chromosome stability. Strome ED, et al. Genetics, 2008 Mar. PMID 18245329, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial genome maintenance IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mitochondrion organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitochondrion organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in plasmid maintenance IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion HDA PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Dml1p
    NP_013938.1
    • Essential protein involved in mtDNA inheritance; may also function in the partitioning of the mitochondrial organelle or in the segregation of chromosomes, exhibits regions similar to members of a GTPase family

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3 Reference assembly

      Range
      689083..690510
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182718.1 → NP_013938.1  TPA: Dml1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013938.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W036, Q03652
      UniProtKB/TrEMBL
      A6ZMS3, B3LM99, C7GRE0, C8ZF75
      Conserved Domains (1) summary
      cl10017
      Location:2 → 290
      Tubulin_FtsZ_Cetz-like; Tubulin protein family of FtsZ and CetZ-like
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q03652.1

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