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    ENB1 Enb1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854007, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ENB1
    Official Full Name
    Enb1p
    Primary source
    SGD:S000005518
    Locus tag
    YOL158C
    See related
    AllianceGenome:SGD:S000005518; FungiDB:YOL158C; VEuPathDB:YOL158C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    ARN4
    Summary
    Enables ferric-enterobactin transmembrane transporter activity. Involved in ferric-enterobactin import into cell. Located in cellular bud membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ENB1 in Genome Data Viewer
    Location:
    chromosome: XV
    Exon count:
    1
    Sequence:
    Chromosome: XV; NC_001147.6 (19491..21311, complement)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Css3p Neighboring gene oligo-1,6-glucosidase IMA2 Neighboring gene hexose transporter HXT11

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001147.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A gene of the major facilitator superfamily encodes a transporter for enterobactin (Enb1p) in Saccharomyces cerevisiae. Heymann P, et al. Biometals, 2000 Mar. PMID 10831226
    2. Relationship between chloroquine toxicity and iron acquisition in Saccharomyces cerevisiae. Emerson LR, et al. Antimicrob Agents Chemother, 2002 Mar. PMID 11850263, Free PMC Article
    3. Linking the dynamics of chromatin occupancy and transcription with predictive models. Tran TQ, et al. Genome Res, 2021 Jun. PMID 33893157, Free PMC Article
    4. Trafficking of siderophore transporters in Saccharomyces cerevisiae and intracellular fate of ferrioxamine B conjugates. Froissard M, et al. Traffic, 2007 Nov. PMID 17714436, Free PMC Article
    5. Cellular iron utilization is regulated by putative siderophore transporter FgSit1 not by free iron transporter in Fusarium graminearum. Park YS, et al. Biochem Biophys Res Commun, 2006 Jul 14. PMID 16750173

    See all (36) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables ferric-enterobactin transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables siderophore-iron transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in ferric-enterobactin import into cell IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in intracellular iron ion homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in iron ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in siderophore transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cell periphery HDA PubMed 
    located_in cellular bud membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endosome membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in fungal-type vacuole HDA PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in vacuolar membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Enb1p
    NP_014484.1
    • Ferric enterobactin transmembrane transporter; expressed under conditions of iron deprivation; member of the major facilitator superfamily; expression is regulated by Rcs1p and affected by chloroquine treatment

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      19491..21311 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183411.1 → NP_014484.1  TPA: Enb1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014484.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W1R2, Q08299
      UniProtKB/TrEMBL
      B5VR99, N1NXM6
      Conserved Domains (1) summary
      cd17322
      Location:63 → 574
      MFS_ARN_like; Yeast ARN family of Siderophore iron transporters and similar proteins of the Major Facilitator Superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q08299.1

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