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    YAP7 Yap7p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854129, updated on 14-Nov-2024

    Summary

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    Official Symbol
    YAP7
    Official Full Name
    Yap7p
    Primary source
    SGD:S000005388
    Locus tag
    YOL028C
    See related
    AllianceGenome:SGD:S000005388; FungiDB:YOL028C; VEuPathDB:YOL028C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables sequence-specific DNA binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See YAP7 in Genome Data Viewer
    Location:
    chromosome: XV
    Exon count:
    1
    Sequence:
    Chromosome: XV; NC_001147.6 (270633..271370, complement)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene 1,3-beta-glucanosyltransferase Neighboring gene uncharacterized protein Neighboring gene ribosome-binding protein MDM38 Neighboring gene Mim1p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001147.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. De novo identification and biophysical characterization of transcription-factor binding sites with microfluidic affinity analysis. Fordyce PM, et al. Nat Biotechnol, 2010 Sep. PMID 20802496, Free PMC Article
    2. Yap7 is a transcriptional repressor of nitric oxide oxidase in yeasts, which arose from neofunctionalization after whole genome duplication. Merhej J, et al. Mol Microbiol, 2015 Jun. PMID 25732006
    3. Yap, a novel family of eight bZIP proteins in Saccharomyces cerevisiae with distinct biological functions. Fernandes L, et al. Mol Cell Biol, 1997 Dec. PMID 9372930, Free PMC Article
    4. Analysis of the DNA sequence of a 34,038 bp region on the left arm of yeast chromosome XV. Rad MR, et al. Yeast, 1997 Mar 15. PMID 9090058
    5. A strategy for interaction site prediction between phospho-binding modules and their partners identified from proteomic data. Aucher W, et al. Mol Cell Proteomics, 2010 Dec. PMID 20733106, Free PMC Article

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables transcription cis-regulatory region binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase II ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IC
    Inferred by Curator
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Yap7p
    NP_014614.1
    • Transcriptional repressor of nitric oxide oxidase; basic leucine zipper (bZIP) transcription factor; neighboring gene, YOL029C, created by frame-shift at position 708, corresponds to C-terminal part of YAP7 orthologs in other species; YAP7 has a paralog, YAP5, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      270633..271370 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183282.1 → NP_014614.1  TPA: Yap7p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014614.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W237, Q08182
      UniProtKB/TrEMBL
      B3LJ29, B5VRM3, N1NVP8
      Conserved Domains (2) summary
      cd14688
      Location:126 → 188
      bZIP_YAP; Basic leucine zipper (bZIP) domain of Yeast Activator Protein (YAP) and similar proteins: a DNA-binding and dimerization domain
      pfam10297
      Location:50 → 66
      Hap4_Hap_bind; Minimal binding motif of Hap4 for binding to Hap2/3/5
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q08182.1

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