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    CG1271 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38364, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG1271provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0035392
    Locus tag
    Dmel_CG1271
    See related
    AllianceGenome:FB:FBgn0035392
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG1271
    Summary
    Predicted to be involved in glycerol metabolic process; glycerol-3-phosphate biosynthetic process; and triglyceride metabolic process. Predicted to be active in mitochondrion. Is expressed in adult head. Orthologous to human GK5 (glycerol kinase 5). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG1271 in Genome Data Viewer
    Location:
    63A5-63A5; 3-5 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (3052514..3054906)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (3052514..3054906)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Sphingosine kinase 2 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Conserved family of glycerol kinase loci in Drosophila melanogaster. Martinez Agosto JA, et al. Mol Genet Metab, 2006 Aug. PMID 16545593, Free PMC Article
    2. CRISPR/Cas9 mediated genetic resource for unknown kinase and phosphatase genes in Drosophila. Wu M, et al. Sci Rep, 2020 Apr 30. PMID 32355295, Free PMC Article
    3. Gliogenesis in Drosophila: genome-wide analysis of downstream genes of glial cells missing in the embryonic nervous system. Egger B, et al. Development, 2002 Jul. PMID 12091301
    4. Identification of genes that promote or inhibit olfactory memory formation in Drosophila. Walkinshaw E, et al. Genetics, 2015 Apr. PMID 25644700, Free PMC Article
    5. Microbiota-induced changes in drosophila melanogaster host gene expression and gut morphology. Broderick NA, et al. mBio, 2014 May 27. PMID 24865556, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    NOT enables glycerol kinase activity IKR
    Inferred from Key Residues
    more info
    		 PubMed 
    NOT enables transferase activity IKR
    Inferred from Key Residues
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in glycerol metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in glycerol-3-phosphate biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in triglyceride metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG1271-PA
    CG1271-PB
    CG1271-PC
    CG1271-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      3052514..3054906
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_206259.2 → NP_995981.1  uncharacterized protein Dmel_CG1271, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_995981.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7KV84
      Conserved Domains (2) summary
      COG0554
      Location:50 → 315
      GlpK; Glycerol kinase [Energy production and conversion]
      cl17037
      Location:1 → 345
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    2. NM_167974.2 → NP_728796.1  uncharacterized protein Dmel_CG1271, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_728796.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8I939
      Related
      FBpp0072856
      Conserved Domains (2) summary
      COG0554
      Location:50 → 405
      GlpK; Glycerol kinase [Energy production and conversion]
      cl17037
      Location:1 → 402
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    3. NM_139506.3 → NP_647763.1  uncharacterized protein Dmel_CG1271, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_647763.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7YTX2, Q95S17, Q9VZV9
      Related
      FBpp0072857
      Conserved Domains (2) summary
      cd07793
      Location:32 → 552
      FGGY_GK5_metazoa; metazoan glycerol kinase 5-like proteins; belongs to the FGGY family of carbohydrate kinases
      COG0554
      Location:32 → 555
      GlpK; Glycerol kinase [Energy production and conversion]

    4. NM_167973.2 → NP_728795.1  uncharacterized protein Dmel_CG1271, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_728795.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7YTX2, Q8I940
      Related
      FBpp0072858
      Conserved Domains (2) summary
      cd07793
      Location:32 → 535
      FGGY_GK5_metazoa; metazoan glycerol kinase 5-like proteins; belongs to the FGGY family of carbohydrate kinases
      COG0554
      Location:32 → 538
      GlpK; Glycerol kinase [Energy production and conversion]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7KV84 Q7KV84
    Q7YTX2 Q7YTX2
    Q8I939 Q8I939
    Q8I940 Q8I940
    Q8IGI3 Q8IGI3
    Q9VZV9 Q9VZV9

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