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    CG16710 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42790, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG16710provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039101
    Locus tag
    Dmel_CG16710
    See related
    AllianceGenome:FB:FBgn0039101
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    cSP16; Dmel\CG16710; SP16
    Summary
    Predicted to enable serine-type endopeptidase activity. Predicted to be involved in innate immune response and proteolysis. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG16710 in Genome Data Viewer
    Location:
    95A7-95A7; 3-80 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (23682503..23683980)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (19508225..19509702)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Gamma-interferon-inducible lysosomal thiol reductase 2 Neighboring gene eukaryotic translation initiation factor 3 subunit d1 Neighboring gene uncharacterized protein Neighboring gene Spatzle-Processing Enzyme Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR43903

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Spätzle-Processing Enzyme-independent Activation of the Toll Pathway in Drosophila Innate Immunity. Yamamoto-Hino M, et al. Cell Struct Funct, 2016 May 7. PMID 26843333
    2. Genetic evidence of a redox-dependent systemic wound response via Hayan protease-phenoloxidase system in Drosophila. Nam HJ, et al. EMBO J, 2012 Mar 7. PMID 22227521, Free PMC Article
    3. Drosophila melanogaster clip-domain serine proteases: Structure, function and regulation. Veillard F, et al. Biochimie, 2016 Mar. PMID 26453810
    4. Enhanced function annotations for Drosophila serine proteases: a case study for systematic annotation of multi-member gene families. Shah PK, et al. Gene, 2008 Jan 15. PMID 17996400
    5. Serine proteases and their homologs in the Drosophila melanogaster genome: an initial analysis of sequence conservation and phylogenetic relationships. Ross J, et al. Gene, 2003 Jan 30. PMID 12568721

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables serine-type endopeptidase activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in innate immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in proteolysis ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG16710-PB
    NP_651167.3

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      23682503..23683980
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142910.3 → NP_651167.3  uncharacterized protein Dmel_CG16710 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651167.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VCJ9
      Conserved Domains (3) summary
      smart00020
      Location:105 → 362
      Tryp_SPc; Trypsin-like serine protease
      cd00190
      Location:106 → 362
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
      pfam12032
      Location:35 → 84
      CLIP; Regulatory CLIP domain of proteinases
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VCJ9 Q9VCJ9

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