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    CG32847 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 318245, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG32847provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0052847
    Locus tag
    Dmel_CG32847
    See related
    AllianceGenome:FB:FBgn0052847
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG32847
    Summary
    Predicted to enable ubiquitin protein ligase activity; ubiquitin-like protein conjugating enzyme binding activity; and zinc ion binding activity. Predicted to be involved in ERAD pathway; protein ubiquitination; and ubiquitin-dependent protein catabolic process. Predicted to be located in endoplasmic reticulum. Orthologous to human RNF185 (ring finger protein 185) and RNF5 (ring finger protein 5). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG32847 in Genome Data Viewer
    Location:
    71B5-71B5; 3-42 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (15121572..15122301)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (15114672..15115401)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene CTP synthase Neighboring gene antisense RNA:CR43971 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Centrosomal protein 135kDa Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene small Cajal body-specific RNA : MeU5-U42 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Suppression of retinal degeneration by two novel ERAD ubiquitin E3 ligases SORDD1/2 in Drosophila. Xu J, et al. PLoS Genet, 2020 Nov. PMID 33137101, Free PMC Article
    2. Age-dependent chromosomal distribution of male-biased genes in Drosophila. Zhang YE, et al. Genome Res, 2010 Nov. PMID 20798392, Free PMC Article
    3. A cautionary note for retrocopy identification: DNA-based duplication of intron-containing genes significantly contributes to the origination of single exon genes. Zhang YE, et al. Bioinformatics, 2011 Jul 1. PMID 21551137, Free PMC Article
    4. Retrogene movement within- and between-chromosomes in the evolution of Drosophila genomes. Dai H, et al. Gene, 2006 Dec 30. PMID 17101240
    5. Comprehensively surveying structure and function of RING domains from Drosophila melanogaster. Ying M, et al. PLoS One, 2011. PMID 21912646, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ubiquitin protein ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ubiquitin-like protein conjugating enzyme binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ubiquitin-protein transferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables zinc ion binding ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in ERAD pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein ubiquitination ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG32847-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      15121572..15122301
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_168609.2 → NP_730026.1  uncharacterized protein Dmel_CG32847 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_730026.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IQM1
      Related
      FBpp0075392
      Conserved Domains (2) summary
      PLN03208
      Location:4 → 91
      PLN03208; E3 ubiquitin-protein ligase RMA2; Provisional
      cd00162
      Location:17 → 60
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8IQM1 Q8IQM1

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