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    Cmtm1 CKLF-like MARVEL transmembrane domain containing 1 [ Mus musculus (house mouse) ]

    Gene ID: 100504164, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Cmtm1provided by MGI
    Official Full Name
    CKLF-like MARVEL transmembrane domain containing 1provided by MGI
    Primary source
    MGI:MGI:2447159
    See related
    Ensembl:ENSMUSG00000110430 AllianceGenome:MGI:2447159
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    CKLFH; CKLFH1; CHLFH1a; Cklfsf1
    Summary
    Predicted to be active in membrane. Orthologous to human CMTM1 (CKLF like MARVEL transmembrane domain containing 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward testis adult (RPKM 35.0) See more
    Orthologs
    human all
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    Genomic context

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    See Cmtm1 in Genome Data Viewer
    Location:
    8 D3; 8 53.04 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (105020174..105036777, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (104293542..104310145, complement)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene chemokine-like factor Neighboring gene STARR-seq mESC enhancer starr_22506 Neighboring gene CKLF-like MARVEL transmembrane domain containing 2A Neighboring gene predicted gene 45710 Neighboring gene CKLF-like MARVEL transmembrane domain containing 2B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Co-expression of sperm membrane proteins CMTM2A and CMTM2B is essential for ADAM3 localization and male fertility in mice. Fujihara Y, et al. J Cell Sci, 2018 Oct 8. PMID 30209135, Free PMC Article
    2. Identification of eight genes encoding chemokine-like factor superfamily members 1-8 (CKLFSF1-8) by in silico cloning and experimental validation. Han W, et al. Genomics, 2003 Jun. PMID 12782130
    3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    CKLF-like MARVEL transmembrane domain-containing protein 1
    Names
    chemokine-like factor super family 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_181990.2 → NP_871790.2  CKLF-like MARVEL transmembrane domain-containing protein 1

      See identical proteins and their annotated locations for NP_871790.2

      Status: VALIDATED

      Source sequence(s)
      AC121275, AC121952
      Consensus CDS
      CCDS57636.1
      UniProtKB/TrEMBL
      B7ZP21
      Related
      ENSMUSP00000124855.2, ENSMUST00000159039.2
      Conserved Domains (2) summary
      pfam01284
      Location:172 → 274
      MARVEL; Membrane-associating domain
      pfam07001
      Location:30 → 108
      BAT2_N; BAT2 N-terminus

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      105020174..105036777 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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