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    comm3 comm3 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39696, updated on 9-Dec-2024

    Summary

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    Official Symbol
    comm3provided by FlyBase
    Official Full Name
    comm3provided by FlyBase
    Primary source
    FLYBASE:FBgn0259236
    Locus tag
    Dmel_CG42334
    See related
    AllianceGenome:FB:FBgn0259236
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG13446; CG13447; CG13448; CG33209; CG42334; Dmel\CG42334
    Old locus tag
    Dmel_CG13446; Dmel_CG33209
    Summary
    Predicted to be involved in axon guidance. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See comm3 in Genome Data Viewer
    Location:
    71E3-71E5; 3-43 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (15613184..15647762, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (15606284..15640862, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Rho GTPase activating protein at 71E Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Phaser Neighboring gene long non-coding RNA:CR45977 Neighboring gene uncharacterized protein Neighboring gene Ecdysone-induced gene 71Ea

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Comm sorts robo to control axon guidance at the Drosophila midline. Keleman K, et al. Cell, 2002 Aug 23. PMID 12202032
    2. The WAGR syndrome gene PRRG4 is a functional homologue of the commissureless axon guidance gene. Justice ED, et al. PLoS Genet, 2017 Aug. PMID 28859078, Free PMC Article
    3. Screening of suppressors of bax-induced cell death identifies glycerophosphate oxidase-1 as a mediator of debcl-induced apoptosis in Drosophila. Colin J, et al. Genes Cancer, 2015 May. PMID 26124923, Free PMC Article
    4. Genetic architecture of natural variation in visual senescence in Drosophila. Carbone MA, et al. Proc Natl Acad Sci U S A, 2016 Oct 25. PMID 27791033, Free PMC Article
    5. A SAGE approach to discovery of genes involved in autophagic cell death. Gorski SM, et al. Curr Biol, 2003 Feb 18. PMID 12593804

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in axon guidance IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    comm3
    Names
    CG42334-PC
    CG42334-PD
    CG42334-PE
    comm3-PC
    comm3-PD
    comm3-PE

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      15613184..15647762 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140534.3 → NP_648791.2  comm3, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648791.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q29QI2, Q9VUS2
      Conserved Domains (1) summary
      pfam15957
      Location:69 → 202
      Comm; Commissureless

    2. NM_001300143.1 → NP_001287072.1  comm3, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287072.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4V6T5, Q9VUS1
      Conserved Domains (1) summary
      pfam15957
      Location:144 → 247
      Comm; Commissureless

    3. NM_176331.2 → NP_788509.1  comm3, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788509.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4V6T5, Q9VUS1
      Related
      FBpp0289129
      Conserved Domains (1) summary
      pfam15957
      Location:144 → 247
      Comm; Commissureless
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q2XY92 Q2XY92
    Q9VUS1 Q9VUS1
    Q9VUS2 Q9VUS2

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