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    NLRP3 NLR family pyrin domain containing 3 [ Gorilla gorilla gorilla (western lowland gorilla) ]

    Gene ID: 101125506, updated on 14-Nov-2024

    Summary

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    Gene symbol
    NLRP3
    Gene description
    NLR family pyrin domain containing 3
    See related
    Ensembl:ENSGGOG00000004835
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gorilla gorilla gorilla (sub-species: gorilla)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Gorilla
    Also known as
    CIAS1; cryopyrin
    Orthologs
    human mouse all
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    Genomic context

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    See NLRP3 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mGorGor1-v2.0_pri (GCF_029281585.2) 1 NC_073224.2 (7981504..8069850, complement)
    RS_2023_04 previous assembly NHGRI_mGorGor1-v1.1-0.2.freeze_pri (GCF_029281585.1) 1 NC_073224.1 (240386223..240474592)

    Chromosome 1 - NC_073224.2Genomic Context describing neighboring genes Neighboring gene putative olfactory receptor 2W5 Neighboring gene olfactory receptor 2B11 Neighboring gene uncharacterized LOC129532292 Neighboring gene zinc finger protein 496 Neighboring gene vomeronasal type-1 receptor 5-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in inflammatory response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of acute inflammatory response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of non-canonical NF-kappaB signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of NLRP3 inflammasome complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    NACHT, LRR and PYD domains-containing protein 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_029281585.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mGorGor1-v2.0_pri Primary Assembly

    Genomic

    1. NC_073224.2 Reference NHGRI_mGorGor1-v2.0_pri Primary Assembly

      Range
      7981504..8069850 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063706965.1 → XP_063563035.1  NACHT, LRR and PYD domains-containing protein 3 isoform X1

    2. XM_063706966.1 → XP_063563036.1  NACHT, LRR and PYD domains-containing protein 3 isoform X1

    3. XM_063706969.1 → XP_063563039.1  NACHT, LRR and PYD domains-containing protein 3 isoform X1

    4. XM_063706976.1 → XP_063563046.1  NACHT, LRR and PYD domains-containing protein 3 isoform X1

    5. XM_055380897.2 → XP_055236872.1  NACHT, LRR and PYD domains-containing protein 3 isoform X1

    6. XM_063706980.1 → XP_063563050.1  NACHT, LRR and PYD domains-containing protein 3 isoform X2

    Nucleotide Protein
    Heading Accession and Version

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