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    Pp1-13C Protein phosphatase 1 at 13C [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 48531, updated on 9-Dec-2024

    Summary

    Official Symbol
    Pp1-13Cprovided by FlyBase
    Official Full Name
    Protein phosphatase 1 at 13Cprovided by FlyBase
    Primary source
    FLYBASE:FBgn0003132
    Locus tag
    Dmel_CG9156
    See related
    AllianceGenome:FB:FBgn0003132
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    13C; CG9156; Dmel\CG9156; DmPp1-13C; Pp1; PP1; PP1 13C; PP1 beta13c; pp1-13C; PP1-13C; PP13C; PP1alpha-13C; PP1alpha13C; PP1c
    Summary
    Enables protein serine/threonine phosphatase activity. Involved in negative regulation of smoothened signaling pathway. Part of protein phosphatase type 1 complex. Is expressed in adult heart; spermatozoon; and testis. Orthologous to human PPP1CA (protein phosphatase 1 catalytic subunit alpha). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
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    Genomic context

    See Pp1-13C in Genome Data Viewer
    Location:
    13B9-13B9; 1-50 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (15359101..15361061, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (15253134..15255094, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene pre-mRNA processing factor 5 Neighboring gene abnormal chemosensory jump 6 Neighboring gene uncharacterized protein Neighboring gene Cyclic nucleotide-gated ion channel-like

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein serine/threonine phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein serine/threonine phosphatase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of BMP signaling pathway IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in negative regulation of smoothened signaling pathway IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in regulation of glycogen biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulation of glycogen catabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of protein phosphatase type 1 complex IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    protein phosphatase 1 at 13C
    Names
    CG9156-PA
    Pp1-13C-PA
    protein phosphatase 1
    protein phosphatase 1 13C
    NP_524921.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      15359101..15361061 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_080182.3NP_524921.1  protein phosphatase 1 at 13C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_524921.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q05547, Q9VXW0
      UniProtKB/TrEMBL
      B4F4X2, C0MKX3
      Related
      FBpp0073834
      Conserved Domains (2) summary
      PTZ00480
      Location:5299
      PTZ00480; serine/threonine-protein phosphatase; Provisional
      cd07414
      Location:6296
      MPP_PP1_PPKL; PP1, PPKL (PP1 and kelch-like) enzymes, and related proteins, metallophosphatase domain