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    CG5071 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43090, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG5071provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039347
    Locus tag
    Dmel_CG5071
    See related
    AllianceGenome:FB:FBgn0039347
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:AT31683; Dmel\CG5071
    Summary
    Predicted to enable cyclosporin A binding activity; peptidyl-prolyl cis-trans isomerase activity; and zinc ion binding activity. Predicted to be involved in protein folding. Predicted to be active in cytoplasm. Is expressed in spermatozoon. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG5071 in Genome Data Viewer
    Location:
    96E5-96E5; 3-88 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (25618414..25621838)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (21444136..21446401)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene musashi Neighboring gene yellow-emperor Neighboring gene uncharacterized protein Neighboring gene Nuclear protein localization 4 Neighboring gene Succinic semialdehyde dehydrogenase Neighboring gene jing interacting gene regulatory 1 Neighboring gene mir-92a stem loop

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Segmental duplication, microinversion, and gene loss associated with a complex inversion breakpoint region in Drosophila. Calvete O, et al. Mol Biol Evol, 2012 Jul. PMID 22328714, Free PMC Article
    2. Genomic analysis of the TRIM family reveals two groups of genes with distinct evolutionary properties. Sardiello M, et al. BMC Evol Biol, 2008 Aug 1. PMID 18673550, Free PMC Article
    3. Comprehensively surveying structure and function of RING domains from Drosophila melanogaster. Ying M, et al. PLoS One, 2011. PMID 21912646, Free PMC Article
    4. A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Neely GG, et al. Cell, 2010 Nov 12. PMID 21074052, Free PMC Article
    5. High-fidelity promoter profiling reveals widespread alternative promoter usage and transposon-driven developmental gene expression. Batut P, et al. Genome Res, 2013 Jan. PMID 22936248, Free PMC Article

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables cyclosporin A binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables peptidyl-prolyl cis-trans isomerase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables peptidyl-prolyl cis-trans isomerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein folding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein peptidyl-prolyl isomerization IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG5071-PA
    CG5071-PB
    CG5071-PC
    CG5071-PD
    NP_001247305.1
    NP_001303432.1
    NP_651406.1
    NP_733111.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      25618414..25621838
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001316503.1 → NP_001303432.1  uncharacterized protein Dmel_CG5071, isoform D [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IMS5
      Conserved Domains (2) summary
      cd00162
      Location:16 → 59
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      cl00197
      Location:514 → 674
      cyclophilin; cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the ...

    2. NM_143149.2 → NP_651406.1  uncharacterized protein Dmel_CG5071, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651406.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IMS5
      Related
      FBpp0084258
      Conserved Domains (2) summary
      cd00162
      Location:16 → 59
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      cl00197
      Location:514 → 674
      cyclophilin; cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the ...

    3. NM_170232.2 → NP_733111.1  uncharacterized protein Dmel_CG5071, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_733111.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B6IDI3, Q9VBP7
      Related
      FBpp0084259
      Conserved Domains (1) summary
      cd00162
      Location:16 → 59
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...

    4. NM_001260376.1 → NP_001247305.1  uncharacterized protein Dmel_CG5071, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001247305.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4K7U6, B6IDI3
      Conserved Domains (1) summary
      cd00162
      Location:16 → 59
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4K7U6 A0A0B4K7U6
    Q5BHU6 Q5BHU6
    Q8IH80 Q8IH80
    Q8IMS5 Q8IMS5
    Q8T8Y0 Q8T8Y0
    Q9VBP7 Q9VBP7

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