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    CG17075 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33191, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG17075provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031239
    Locus tag
    Dmel_CG17075
    See related
    AllianceGenome:FB:FBgn0031239
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG17075
    Summary
    Predicted to enable protein-cysteine S-palmitoyltransferase activity. Predicted to be involved in protein targeting to membrane. Located in endoplasmic reticulum. Is expressed in larval central nervous system. Orthologous to human ZDHHC1 (zinc finger DHHC-type containing 1); ZDHHC11 (zinc finger DHHC-type containing 11); and ZDHHC11B (zinc finger DHHC-type containing 11B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG17075 in Genome Data Viewer
    Location:
    21B6-21B7; 2-0.5 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (259949..267505, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (259949..267505, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene kismet Neighboring gene long non-coding RNA:CR44218 Neighboring gene RNaseP protein p30 Neighboring gene Dihydrouridine synthase 1 Neighboring gene long non-coding RNA:CR44219 Neighboring gene uncharacterized protein Neighboring gene mushroom body miniature

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Gain of function screen of PATs reveals an essential role of Hip14 in Drosophila host defense. Deng Z, et al. J Genet Genomics, 2023 Dec. PMID 37343788
    2. The Drosophila protein palmitoylome: characterizing palmitoyl-thioesterases and DHHC palmitoyl-transferases. Bannan BA, et al. Fly (Austin), 2008 Jul-Aug. PMID 18719403, Free PMC Article
    3. Identification of genetic loci that interact with cut during Drosophila wing-margin development. Krupp JJ, et al. Genetics, 2005 Aug. PMID 15956666, Free PMC Article
    4. Rapid and efficient cDNA library screening by self-ligation of inverse PCR products (SLIP). Hoskins RA, et al. Nucleic Acids Res, 2005 Dec 2. PMID 16326860, Free PMC Article
    5. Tissue-specific (ts)CRISPR as an efficient strategy for in vivo screening in Drosophila. Meltzer H, et al. Nat Commun, 2019 May 8. PMID 31068592, Free PMC Article

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables palmitoyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein-cysteine S-palmitoyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein-cysteine S-palmitoyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein targeting to membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG17075-PA
    CG17075-PB
    NP_001245821.1
    NP_608508.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      259949..267505 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001258892.2 → NP_001245821.1  uncharacterized protein Dmel_CG17075, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001245821.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q2XXY4, Q9VPM2
      Conserved Domains (1) summary
      pfam01529
      Location:199 → 282
      zf-DHHC; DHHC palmitoyltransferase

    2. NM_134664.2 → NP_608508.1  uncharacterized protein Dmel_CG17075, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608508.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q2XXY4, Q9VPM2
      Related
      FBpp0077801
      Conserved Domains (1) summary
      pfam01529
      Location:199 → 282
      zf-DHHC; DHHC palmitoyltransferase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q2XXY4 Q2XXY4
    Q9VPM2 Q9VPM2

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