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    glo-2 Biogenesis of lysosome-related organelles complex 1 subunit 6;Biogenesis of lysosome-related organelles complex 1 subunit 7 [ Caenorhabditis elegans ]

    Gene ID: 186447, updated on 9-Dec-2024

    Summary

    Official Symbol
    glo-2
    Official Full Name
    Biogenesis of lysosome-related organelles complex 1 subunit 6;Biogenesis of lysosome-related organelles complex 1 subunit 7
    Primary source
    WormBase:WBGene00019010
    Locus tag
    CELE_F57C9.3
    See related
    AllianceGenome:WB:WBGene00019010
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Enables protein homodimerization activity. Involved in endosomal transport and positive regulation of intracellular protein transport. Located in endosome. Is expressed in intestine and seam cell. Used to study Hermansky-Pudlak syndrome. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See glo-2 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    4
    Sequence:
    Chromosome: I; NC_003279.8 (4836187..4844966)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene HORMA domain-containing protein Neighboring gene C2H2-type domain-containing protein Neighboring gene C-type LECtin Neighboring gene Putative pyridoxal kinase;pyridoxal kinase Neighboring gene Rho-GAP domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein homodimerization activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in endosomal transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of intracellular protein transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of BLOC-1 complex TAS
    Traceable Author Statement
    more info
    PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in endosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in endosome IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Biogenesis of lysosome-related organelles complex 1 subunit 6;Biogenesis of lysosome-related organelles complex 1 subunit 7
    NP_001293460.1
    • Confirmed by transcript evidence
    NP_491461.3
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      4836187..4844966
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001306531.4NP_001293460.1  Biogenesis of lysosome-related organelles complex 1 subunit 7 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001293460.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      J7JQW0, O01822
      UniProtKB/TrEMBL
      M1ZK00
    2. NM_059060.3NP_491461.3  Biogenesis of lysosome-related organelles complex 1 subunit 6 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491461.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O01822