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    snf21 RSC-type complex ATPase Snf21 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542638, updated on 18-Sep-2024

    Summary

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    Official Symbol
    snf21
    Official Full Name
    RSC-type complex ATPase Snf21
    Primary source
    PomBase:SPAC1250.01
    Locus tag
    SPOM_SPAC1250.01
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    brg1; SPAC29A4.21
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    Genomic context

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    See snf21 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    2
    Sequence:
    Chromosome: I; NC_003424.3 (5100148..5104177, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ubiquitin conjugating enzyme Ubc14 Neighboring gene ncRNA Neighboring gene TFIIIC subunit Sfc7 Neighboring gene protein mug95 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene elongator complex histone acetyltransferase subunit Elp3 Neighboring gene Ca(2+)/Mn(2+)-transporting P-type ATPase P5 type Cta5

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Conserved roles of chromatin remodellers in cohesin loading onto chromatin. Muñoz S, et al. Curr Genet, 2020 Oct. PMID 32277274, Free PMC Article
    2. Isolation of a novel complex of the SWI/SNF family from Schizosaccharomyces pombe and its effects on in vitro transcription in nucleosome arrays. Bernal G, et al. Mol Cell Biochem, 2007 Sep. PMID 17508131
    3. Essential roles of Snf21, a Swi2/Snf2 family chromatin remodeler, in fission yeast mitosis. Yamada K, et al. Genes Genet Syst, 2008 Oct. PMID 19168987
    4. The chromatin remodeler RSC prevents ectopic CENP-A propagation into pericentromeric heterochromatin at the chromatin boundary. Tsunemine S, et al. Nucleic Acids Res, 2022 Oct 28. PMID 36200823, Free PMC Article
    5. A genetic screen for functional partners of condensin in fission yeast. Robellet X, et al. G3 (Bethesda), 2014 Feb 19. PMID 24362309, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. These data suggest that Snf21 plays an essential role in mitosis possibly functioning in centromeric chromatin.
      Title: Essential roles of Snf21, a Swi2/Snf2 family chromatin remodeler, in fission yeast mitosis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IC
    Inferred by Curator
    more info
    		  
    enables DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables chromatin-protein adaptor activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables histone binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables histone octamer slider activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables nucleosome array spacer activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in heterochromatin boundary formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in heterochromatin formation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitotic sister chromatid cohesion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in transcription initiation-coupled chromatin remodeling IC
    Inferred by Curator
    more info
    		  
    Component Evidence Code Pubs
    part_of RSC-type complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chromatin IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    RSC-type complex ATPase Snf21

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      5100148..5104177 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001020290.3 → NP_594861.1  RSC-type complex ATPase Snf21 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594861.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O14024, Q9UTN6
      Conserved Domains (7) summary
      cd05519
      Location:1066 → 1168
      Bromo_SNF2; Bromodomain, SNF2-like subfamily, specific to fungi. SNF2 is a yeast protein involved in transcriptional activation, it is the catalytic component of the SWI/SNF ATP-dependent chromatin remodeling complex. The protein is essential for the regulation of ...
      smart00573
      Location:256 → 328
      HSA; domain in helicases and associated with SANT domains
      COG0553
      Location:160 → 894
      HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
      COG5076
      Location:1028 → 1197
      COG5076; Transcription factor involved in chromatin remodeling, contains bromodomain [Chromatin structure and dynamics / Transcription]
      cd00046
      Location:437 → 576
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      pfam00271
      Location:735 → 850
      Helicase_C; Helicase conserved C-terminal domain
      pfam14619
      Location:946 → 1012
      SnAC; Snf2-ATP coupling, chromatin remodelling complex
    Nucleotide Protein
    Heading Accession and Version

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