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    CG14710 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41393, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG14710provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037920
    Locus tag
    Dmel_CG14710
    See related
    AllianceGenome:FB:FBgn0037920
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG14710
    Summary
    Enables DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in organism. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG14710 in Genome Data Viewer
    Location:
    86E13-86E13; 3-51 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (11620090..11621728)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (7445812..7447450)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene jupiter Neighboring gene ZAD and Architectural Function 1 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Jupiter, a new Drosophila protein associated with microtubules. Karpova N, et al. Cell Motil Cytoskeleton, 2006 May. PMID 16518797
    2. Global analysis of target genes of 21 members of the ZAD transcription factor family in Drosophila melanogaster. Krystel J, et al. Gene, 2013 Jan 10. PMID 23085320, Free PMC Article
    3. Twenty-seven ZAD-ZNF genes of Drosophila melanogaster are orthologous to the embryo polarity determining mosquito gene cucoid. Li M, et al. PLoS One, 2023. PMID 36595500, Free PMC Article
    4. Functional variants identify sex-specific genes and pathways in Alzheimer's Disease. Bourquard T, et al. Nat Commun, 2023 May 13. PMID 37179358, Free PMC Article
    5. Innovation of heterochromatin functions drives rapid evolution of essential ZAD-ZNF genes in Drosophila. Kasinathan B, et al. Elife, 2020 Nov 10. PMID 33169670, Free PMC Article

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA-binding transcription activator activity, RNA polymerase II-specific ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG14710-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      11620090..11621728
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141835.5 → NP_650092.4  uncharacterized protein Dmel_CG14710 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650092.4

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7KSP9, Q95RA7, Q9VGL4
      Conserved Domains (5) summary
      COG5048
      Location:261 → 395
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:292 → 312
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:290 → 312
      zf-C2H2; Zinc finger, C2H2 type
      pfam07776
      Location:9 → 83
      zf-AD; Zinc-finger associated domain (zf-AD)
      pfam13465
      Location:304 → 327
      zf-H2C2_2; Zinc-finger double domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7KSP9 Q7KSP9
    Q95RA7 Q95RA7

    Gene LinkOut

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