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    bond james bond [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42657, updated on 9-Dec-2024

    Summary

    Official Symbol
    bondprovided by FlyBase
    Official Full Name
    james bondprovided by FlyBase
    Primary source
    FLYBASE:FBgn0260942
    Locus tag
    Dmel_CG6921
    See related
    AllianceGenome:FB:FBgn0260942
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Bond; CG6921; Dmel\CG6921; James bond
    Summary
    Enables fatty acid elongase activity. Involved in several processes, including cytoskeleton-dependent cytokinesis; fatty acid biosynthetic process; and spindle organization. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum membrane. Is expressed in several structures, including adult head; ganglia; gland; gonad; and gut section. Orthologous to human ELOVL1 (ELOVL fatty acid elongase 1) and ELOVL7 (ELOVL fatty acid elongase 7). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
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    Genomic context

    See bond in Genome Data Viewer
    Location:
    94B4-94B4; 3-75 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (22550680..22556494)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (18376402..18382216)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45647 Neighboring gene Adiponectin receptor Neighboring gene antisense RNA:CR44062 Neighboring gene stuck in traffic Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables fatty acid elongase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables fatty acid elongase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables fatty acid elongase activity IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in actomyosin contractile ring assembly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in fatty acid elongation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in fatty acid elongation, monounsaturated fatty acid IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in fatty acid elongation, polyunsaturated fatty acid IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in fatty acid elongation, saturated fatty acid IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in male meiosis cytokinesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in meiosis I cytokinesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in meiosis II cytokinesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in meiotic spindle organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in pheromone biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in sphingolipid biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in spindle assembly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in very long-chain fatty acid biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in very long-chain fatty acid biosynthetic process IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in very long-chain fatty acid biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    PubMed 

    General protein information

    Preferred Names
    james bond
    Names
    CG6921-PA
    CG6921-PB
    CG6921-PC
    bond-PA
    bond-PB
    bond-PC
    NP_651062.3
    NP_732761.1
    NP_732762.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      22550680..22556494
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142805.4NP_651062.3  james bond, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651062.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      C6SV14, Q9VCY7
      Related
      FBpp0083654
      Conserved Domains (1) summary
      pfam01151
      Location:27262
      ELO; GNS1/SUR4 family
    2. NM_170022.2NP_732761.1  james bond, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732761.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      C6SV14, Q9VCY7
      Related
      FBpp0083655
      Conserved Domains (1) summary
      pfam01151
      Location:27262
      ELO; GNS1/SUR4 family
    3. NM_170023.2NP_732762.1  james bond, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732762.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      C6SV14, Q9VCY7
      Related
      FBpp0083656
      Conserved Domains (1) summary
      pfam01151
      Location:27262
      ELO; GNS1/SUR4 family