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    AQP aquaporin [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36456, updated on 9-Dec-2024

    Summary

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    Official Symbol
    AQPprovided by FlyBase
    Official Full Name
    aquaporinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0033807
    Locus tag
    Dmel_CG12251
    See related
    AllianceGenome:FB:FBgn0033807
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Aqp 12L; AQP-dr; CG12251; Dmel\CG12251
    Summary
    Predicted to enable channel activity. Predicted to be active in cytoplasm. Is expressed in adult head. Orthologous to several human genes including AQP12A (aquaporin 12A) and AQP12B (aquaporin 12B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See AQP in Genome Data Viewer
    Location:
    49F9-49F10; 2-68 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (13212405..13214496, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (9099910..9102001, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Origin recognition complex subunit 3 Neighboring gene FLICE-associated huge protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Aquaporin subfamily with unusual NPA boxes. Ishibashi K. Biochim Biophys Acta, 2006 Aug. PMID 16579962
    2. Insect glycerol transporters evolved by functional co-option and gene replacement. Finn RN, et al. Nat Commun, 2015 Jul 17. PMID 26183829, Free PMC Article
    3. Function-informed transcriptome analysis of Drosophila renal tubule. Wang J, et al. Genome Biol, 2004. PMID 15345053, Free PMC Article
    4. Adult and Larval Tracheal Systems Exhibit Different Molecular Architectures in Drosophila. Bossen J, et al. Int J Mol Sci, 2023 Mar 15. PMID 36982710, Free PMC Article
    5. The genetic basis for variation in olfactory behavior in Drosophila melanogaster. Arya GH, et al. Chem Senses, 2015 May. PMID 25687947, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    aquaporin
    Names
    AQP-PA
    AQP-PB
    CG12251-PA
    CG12251-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      13212405..13214496 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001169669.2 → NP_001163140.1  aquaporin, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001163140.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E1JH55

    2. NM_079004.5 → NP_523728.1  aquaporin, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_523728.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7KY01
      Related
      FBpp0086879
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    E1JH55 E1JH55
    Q7KY01 Q7KY01

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