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    Taf10b TBP-associated factor 10b [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33468, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Taf10bprovided by FlyBase
    Official Full Name
    TBP-associated factor 10bprovided by FlyBase
    Primary source
    FLYBASE:FBgn0026324
    Locus tag
    Dmel_CG3069
    See related
    AllianceGenome:FB:FBgn0026324
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG3069; Dmel\CG3069; dmTAF10b; dTaf10b; dTAF10b; dtafII16; dTAF[[II]]16; TAF; Taf10; taf10b; TAF10b; Taf16; TafII16; TAFII16; TAF[[II]]; TAF[[II]]16; TFIID
    Summary
    Contributes to RNA polymerase II general transcription initiation factor activity. Involved in transcription initiation at RNA polymerase II promoter. Located in cytoplasm and nucleus. Part of SAGA complex and transcription factor TFIID complex. Is expressed in several structures, including anal pad primordium; embryonic cortex; embryonic epidermis; hindgut proper primordium; and midgut primordium. Orthologous to human TAF10 (TATA-box binding protein associated factor 10). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Taf10b in Genome Data Viewer
    Location:
    23A5-23A5; 2-7 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (2767286..2767845, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (2767286..2767845, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Transportin-Serine/Arginine rich Neighboring gene Sorting nexin 21 Neighboring gene anterior pharynx defective 1 Neighboring gene TBP-associated factor 10 Neighboring gene congested-like trachea Neighboring gene histidine triad nucleotide binding protein 1 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TAF10 and TAF10b partially redundant roles during Drosophila melanogaster morphogenesis. Pahi Z, et al. Transcription, 2017. PMID 28841365, Free PMC Article
    2. Study of the properties of two homologues of yeast ADA2 in Drosophila melanogaster. Lebedeva LA, et al. Dokl Biochem Biophys, 2004 Sep-Oct. PMID 15584512
    3. Two novel Drosophila TAF(II)s have homology with human TAF(II)30 and are differentially regulated during development. Georgieva S, et al. Mol Cell Biol, 2000 Mar. PMID 10669741, Free PMC Article
    4. Prodos is a conserved transcriptional regulator that interacts with dTAF(II)16 in Drosophila melanogaster. Hernández-Hernández A, et al. Mol Cell Biol, 2001 Jan. PMID 11134347, Free PMC Article
    5. Control of gene expression through regulation of the TATA-binding protein. Pugh BF. Gene, 2000 Sep 5. PMID 10974559

    See all (65) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    contributes_to RNA polymerase II general transcription initiation factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    contributes_to RNA polymerase II general transcription initiation factor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables promoter-specific chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA-templated transcription initiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transcription initiation at RNA polymerase II promoter IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transcription initiation at RNA polymerase II promoter IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in transcription initiation at RNA polymerase II promoter ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of SAGA complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of SAGA complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of transcription factor TFIID complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of transcription factor TFIID complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of transcription factor TFIID complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    TBP-associated factor 10b
    Names
    CG3069-PA
    TBP-associated factor
    TBP-associated factor 16kD
    Taf10b-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      2767286..2767845 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_058070.6 → NP_477418.1  TBP-associated factor 10b [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_477418.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9XZT7
      Related
      FBpp0077415
      Conserved Domains (1) summary
      cd07982
      Location:41 → 144
      TAF10; The TATA Binding Protein (TBP) Associated Factor 10
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9XZT7.1 Q9XZT7

    Gene LinkOut

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