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    CG17593 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33573, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG17593provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031544
    Locus tag
    Dmel_CG17593
    See related
    AllianceGenome:FB:FBgn0031544
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG17593
    Summary
    Predicted to enable calcium ion binding activity. Predicted to be involved in endoplasmic reticulum calcium ion homeostasis. Located in cytoplasm. Is expressed in several structures, including Malpighian tubule primordium; adult head; embryonic/larval midgut primordium; gut section; and mesoderm. Orthologous to human CCDC47 (coiled-coil domain containing 47). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG17593 in Genome Data Viewer
    Location:
    23F6-23F6; 2-10 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (3514872..3517264)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (3514872..3517264)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR45300 Neighboring gene uncharacterized protein Neighboring gene Leucyl-tRNA synthetase Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Scavenger receptor class C, type IV

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Asymmetric segregation of the tumor suppressor brat regulates self-renewal in Drosophila neural stem cells. Betschinger J, et al. Cell, 2006 Mar 24. PMID 16564014
    2. Drosophila MSL complex globally acetylates H4K16 on the male X chromosome for dosage compensation. Gelbart ME, et al. Nat Struct Mol Biol, 2009 Aug. PMID 19648925, Free PMC Article
    3. Genome-wide analysis of the maternal-to-zygotic transition in Drosophila primordial germ cells. Siddiqui NU, et al. Genome Biol, 2012 Feb 20. PMID 22348290, Free PMC Article
    4. The nucleosome remodeling factor ISWI functionally interacts with an evolutionarily conserved network of cellular factors. Arancio W, et al. Genetics, 2010 May. PMID 20194965, Free PMC Article
    5. Mapping organelle proteins and protein complexes in Drosophila melanogaster. Tan DJ, et al. J Proteome Res, 2009 Jun. PMID 19317464

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables calcium ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in endoplasmic reticulum calcium ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in endomembrane system HDA PubMed 
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG17593-PA
    CG17593-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      3514872..3517264
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001273069.1 → NP_001259998.1  uncharacterized protein Dmel_CG17593, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259998.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SZL8, Q9VQR9
      Conserved Domains (1) summary
      pfam07946
      Location:138 → 463
      DUF1682; Protein of unknown function (DUF1682)

    2. NM_134942.3 → NP_608786.2  uncharacterized protein Dmel_CG17593, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608786.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SZL8, Q9VQR9
      Related
      FBpp0077214
      Conserved Domains (1) summary
      pfam07946
      Location:138 → 463
      DUF1682; Protein of unknown function (DUF1682)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8SZL8 Q8SZL8
    Q9VQR9 Q9VQR9

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