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    TbCMF46 TbCMF46 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34318, updated on 9-Dec-2024

    Summary

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    Official Symbol
    TbCMF46provided by FlyBase
    Official Full Name
    TbCMF46provided by FlyBase
    Primary source
    FLYBASE:FBgn0032163
    Locus tag
    Dmel_CG13125
    See related
    AllianceGenome:FB:FBgn0032163
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG13125; CT32363; Dmel\CG13125; mel CG13125
    Summary
    Colocalizes with cilium. Is expressed in chordotonal neurons; sensory neurons; and spermatogonium. Orthologous to human DRC3 (dynein regulatory complex subunit 3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See TbCMF46 in Genome Data Viewer
    Location:
    30F1-30F1; 2-38 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (9922737..9924865, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (9922737..9924865, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Y chromosome of D. pseudoobscura is not homologous to the ancestral Drosophila Y. Carvalho AB, et al. Science, 2005 Jan 7. PMID 15528405
    2. Evolution of gene sequence in response to chromosomal location. Díaz-Castillo C, et al. Genetics, 2007 Sep. PMID 17890366, Free PMC Article
    3. Many P-element insertions affect wing shape in Drosophila melanogaster. Weber K, et al. Genetics, 2005 Mar. PMID 15545659, Free PMC Article
    4. Identification of novel regulatory factor X (RFX) target genes by comparative genomics in Drosophila species. Laurençon A, et al. Genome Biol, 2007. PMID 17875208, Free PMC Article
    5. Survey of the Ciliary Motility Machinery of Drosophila Sperm and Ciliated Mechanosensory Neurons Reveals Unexpected Cell-Type Specific Variations: A Model for Motile Ciliopathies. Zur Lage P, et al. Front Genet, 2019. PMID 30774648, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Component Evidence Code Pubs
    colocalizes_with cilium IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    TbCMF46
    Names
    CG13125-PA
    TbCMF46-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      9922737..9924865 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135481.3 → NP_609325.2  TbCMF46 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609325.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VL65
      Related
      FBpp0079493
      Conserved Domains (3) summary
      sd00031
      Location:91 → 112
      LRR_1; leucine-rich repeat [structural motif]
      pfam12799
      Location:89 → 131
      LRR_4; Leucine Rich repeats (2 copies)
      pfam13855
      Location:89 → 145
      LRR_8; Leucine rich repeat
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VL65 Q9VL65

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