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    Wfdc13 WAP four-disulfide core domain 13 [ Mus musculus (house mouse) ]

    Gene ID: 408190, updated on 9-Dec-2024

    Summary

    Official Symbol
    Wfdc13provided by MGI
    Official Full Name
    WAP four-disulfide core domain 13provided by MGI
    Primary source
    MGI:MGI:3582777
    See related
    Ensembl:ENSMUSG00000067704 AllianceGenome:MGI:3582777
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Wfdc13l1
    Summary
    Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in antibacterial humoral response and innate immune response. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Orthologous to human WFDC13 (WAP four-disulfide core domain 13). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward genital fat pad adult (RPKM 377.4) See more
    Orthologs
    NEW
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    Genomic context

    See Wfdc13 in Genome Data Viewer
    Location:
    2 H3; 2 85.25 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (164527027..164529626)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (164685107..164687706)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene WAP four-disulfide core domain 9 Neighboring gene WAP four-disulfide core domain 10 Neighboring gene WAP four-disulfide core domain 11 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:164504826-164505027 Neighboring gene serine protease inhibitor, Kunitz type 4 Neighboring gene serine protease inhibitor, Kunitz type 5

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables serine-type endopeptidase inhibitor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables serine-type endopeptidase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in antibacterial humoral response IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in innate immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    WAP four-disulfide core domain protein 13
    Names
    WAP four-disulfide core domain 13-like 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001012704.1NP_001012722.1  WAP four-disulfide core domain protein 13 precursor

      See identical proteins and their annotated locations for NP_001012722.1

      Status: PROVISIONAL

      Source sequence(s)
      AY542486
      Consensus CDS
      CCDS38327.1
      UniProtKB/Swiss-Prot
      Q5DQQ6, Q6IE33
      Related
      ENSMUSP00000085594.2, ENSMUST00000088260.2

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      164527027..164529626
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)