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    Adprh ADP-ribosylarginine hydrolase [ Mus musculus (house mouse) ]

    Gene ID: 11544, updated on 9-Dec-2024

    Summary

    Official Symbol
    Adprhprovided by MGI
    Official Full Name
    ADP-ribosylarginine hydrolaseprovided by MGI
    Primary source
    MGI:MGI:1098234
    See related
    Ensembl:ENSMUSG00000002844 AllianceGenome:MGI:1098234
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Arh1
    Summary
    Enables ADP-ribosylarginine hydrolase activity. Involved in protein modification process. Predicted to be located in extracellular space. Is expressed in cerebral cortex. Orthologous to human ADPRH (ADP-ribosylarginine hydrolase). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in ovary adult (RPKM 55.7), adrenal adult (RPKM 52.6) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Adprh in Genome Data Viewer
    Location:
    16 B3- B4; 16 26.86 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (38265761..38273051, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (38445399..38452689, complement)

    Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr16:38400095-38400248 Neighboring gene phospholipase A1 member A Neighboring gene STARR-positive B cell enhancer ABC_E8634 Neighboring gene STARR-seq mESC enhancer starr_40819 Neighboring gene STARR-seq mESC enhancer starr_40820 Neighboring gene predicted gene, 36333 Neighboring gene STARR-seq mESC enhancer starr_40821 Neighboring gene STARR-positive B cell enhancer ABC_E9931 Neighboring gene STARR-seq mESC enhancer starr_40823 Neighboring gene STARR-positive B cell enhancer ABC_E9164 Neighboring gene CD80 antigen Neighboring gene STARR-seq mESC enhancer starr_40825 Neighboring gene STARR-positive B cell enhancer ABC_E7448 Neighboring gene SET domain-containing protein 8 pseudogene Neighboring gene predicted gene, 41453

    Genomic regions, transcripts, and products

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 
    • Targeted (1)  1 citation

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ADP-ribosylarginine hydrolase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables ADP-ribosylarginine hydrolase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables ADP-ribosylarginine hydrolase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables magnesium ion binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables magnesium ion binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables potassium ion binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables potassium ion binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in protein de-ADP-ribosylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein de-ADP-ribosylation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in protein modification process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in protein modification process ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
     
    located_in extracellular space ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    ADP-ribosylarginine hydrolase
    Names
    ADP-ribose-L-arginine cleaving enzyme
    [Protein ADP-ribosylarginine] hydrolase
    NP_031440.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_007414.3NP_031440.1  ADP-ribosylarginine hydrolase

      See identical proteins and their annotated locations for NP_031440.1

      Status: VALIDATED

      Source sequence(s)
      AK153498, CAAA01037235, CJ155232
      Consensus CDS
      CCDS28167.1
      UniProtKB/Swiss-Prot
      P54923
      UniProtKB/TrEMBL
      Q3U5N4
      Related
      ENSMUSP00000002923.9, ENSMUST00000002923.10
      Conserved Domains (1) summary
      pfam03747
      Location:11328
      ADP_ribosyl_GH; ADP-ribosylglycohydrolase

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000082.7 Reference GRCm39 C57BL/6J

      Range
      38265761..38273051 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)