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    Zbbx zinc finger, B-box domain containing [ Mus musculus (house mouse) ]

    Gene ID: 213234, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Zbbxprovided by MGI
    Official Full Name
    zinc finger, B-box domain containingprovided by MGI
    Primary source
    MGI:MGI:2674085
    See related
    Ensembl:ENSMUSG00000034151 AllianceGenome:MGI:2674085
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4931432L23
    Summary
    Predicted to enable zinc ion binding activity. Is expressed in bladder; central nervous system; female associated reproductive structure; ovary; and urethra of female. Orthologous to human ZBBX (zinc finger B-box domain containing). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward testis adult (RPKM 21.6) See more
    Orthologs
    human all
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    Genomic context

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    See Zbbx in Genome Data Viewer
    Location:
    3 E3; 3 33.72 cM
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (74945202..75072357, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (75037895..75165050, complement)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_07965 Neighboring gene predicted gene, 36069 Neighboring gene STARR-seq mESC enhancer starr_07966 Neighboring gene 40S ribosomal protein S8 pseudogene Neighboring gene STARR-seq mESC enhancer starr_07968 Neighboring gene predicted gene, 40071 Neighboring gene serine (or cysteine) peptidase inhibitor, clade I, member 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract. Wiese CB, et al. Front Neurosci, 2012. PMID 22988430, Free PMC Article
    2. USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities. Liu C, et al. Sci Adv, 2023 May 19. PMID 37196079, Free PMC Article
    3. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
    4. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
    5. GUDMAP: the genitourinary developmental molecular anatomy project. McMahon AP, et al. J Am Soc Nephrol, 2008 Apr. PMID 18287559

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger B-box domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001310529.2 → NP_001297458.1  zinc finger B-box domain-containing protein 1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC121928, AC125332
      Consensus CDS
      CCDS79924.1
      UniProtKB/TrEMBL
      F8WIV1
      Related
      ENSMUSP00000043970.7, ENSMUST00000039269.13
      Conserved Domains (1) summary
      smart00336
      Location:13 → 58
      BBOX; B-Box-type zinc finger

    2. NM_001411534.1 → NP_001398463.1  zinc finger B-box domain-containing protein 1 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC121928, AC125332

    3. NM_172515.4 → NP_766103.2  zinc finger B-box domain-containing protein 1 isoform 1

      See identical proteins and their annotated locations for NP_766103.2

      Status: VALIDATED

      Source sequence(s)
      AC121928, AC125332
      Consensus CDS
      CCDS17412.1
      UniProtKB/Swiss-Prot
      Q0P5X5, Q3V0J2
      Related
      ENSMUSP00000103407.3, ENSMUST00000107778.9
      Conserved Domains (1) summary
      smart00336
      Location:13 → 58
      BBOX; B-Box-type zinc finger

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      74945202..75072357 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006501258.1 → XP_006501321.1  zinc finger B-box domain-containing protein 1 isoform X2

      Conserved Domains (1) summary
      cd19818
      Location:132 → 174
      Bbox1_ZBBX; B-box-type 1 zinc finger found in zinc finger B-box domain-containing protein 1 (ZBBX) and similar proteins

    2. XM_011240063.1 → XP_011238365.1  zinc finger B-box domain-containing protein 1 isoform X3

      Conserved Domains (1) summary
      cd19818
      Location:132 → 174
      Bbox1_ZBBX; B-box-type 1 zinc finger found in zinc finger B-box domain-containing protein 1 (ZBBX) and similar proteins

    3. XM_006501257.1 → XP_006501320.1  zinc finger B-box domain-containing protein 1 isoform X1

      Conserved Domains (1) summary
      cd19818
      Location:132 → 174
      Bbox1_ZBBX; B-box-type 1 zinc finger found in zinc finger B-box domain-containing protein 1 (ZBBX) and similar proteins

    4. XM_036162996.1 → XP_036018889.1  zinc finger B-box domain-containing protein 1 isoform X5

    5. XM_011240064.2 → XP_011238366.1  zinc finger B-box domain-containing protein 1 isoform X6

      See identical proteins and their annotated locations for XP_011238366.1

    6. XM_011240065.2 → XP_011238367.1  zinc finger B-box domain-containing protein 1 isoform X6

      See identical proteins and their annotated locations for XP_011238367.1

    RNA

    1. XR_003954303.1 RNA Sequence

    2. XR_004941300.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q0P5X5.1 GenPept UniProtKB/Swiss-Prot:Q0P5X5

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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