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    neu4 neuraminidase 4 [ Anolis carolinensis (green anole) ]

    Gene ID: 100560635, updated on 8-Mar-2024

    Summary

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    Gene symbol
    neu4
    Gene description
    neuraminidase 4
    See related
    Ensembl:ENSACAG00000000446
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Anolis carolinensis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera; Iguania; Dactyloidae; Anolis
    Orthologs
    human mouse all
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    Genomic context

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    See neu4 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current rAnoCar3.1.pri (GCF_035594765.1) 3 NC_085843.1 (242798018..242805509, complement)
    102 previous assembly AnoCar2.0 (GCF_000090745.1) 3 NC_014778.1 (30666835..30674341)

    Chromosome 3 - NC_085843.1Genomic Context describing neighboring genes Neighboring gene UBX domain protein 7 Neighboring gene transmembrane 4 L six family member 19 Neighboring gene galactose-3-O-sulfotransferase 2 Neighboring gene D-2-hydroxyglutarate dehydrogenase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. New insights on the sialidase protein family revealed by a phylogenetic analysis in metazoa. Giacopuzzi E, et al. PLoS One, 2012. PMID 22952925, Free PMC Article
    2. Gallus gallus NEU3 sialidase as model to study protein evolution mechanism based on rapid evolving loops. Giacopuzzi E, et al. BMC Biochem, 2011 Aug 23. PMID 21861893, Free PMC Article
    3. Cloning and characterization of NEU2, a human gene homologous to rodent soluble sialidases. Monti E, et al. Genomics, 1999 Apr 1. PMID 10191093
    4. Molecular cloning and characterization of NEU4, the fourth member of the human sialidase gene family. Monti E, et al. Genomics, 2004 Mar. PMID 14962670
    5. Identification and expression of NEU3, a novel human sialidase associated to the plasma membrane. Monti E, et al. Biochem J, 2000 Jul 1. PMID 10861246, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables exo-alpha-sialidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in ganglioside catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in oligosaccharide catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in intracellular membrane-bounded organelle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sialidase-4
    Names
    sialidase 4
    NP_001280061.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001293132.1 → NP_001280061.1  sialidase-4

      See identical proteins and their annotated locations for NP_001280061.1

      Status: PROVISIONAL

      Source sequence(s)
      BK008557
      UniProtKB/TrEMBL
      G1K8I1, K0Q6U0
      Related
      ENSACAP00000000394.3, ENSACAT00000000411.3
      Conserved Domains (1) summary
      cd15482
      Location:10 → 476
      Sialidase_non-viral; Non-viral sialidases

    RefSeqs of Annotated Genomes: GCF_035594765.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference rAnoCar3.1.pri

    Genomic

    1. NC_085843.1 Reference rAnoCar3.1.pri

      Range
      242798018..242805509 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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