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    temp tempura [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31212, updated on 9-Dec-2024

    Summary

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    Official Symbol
    tempprovided by FlyBase
    Official Full Name
    tempuraprovided by FlyBase
    Primary source
    FLYBASE:FBgn0027296
    Locus tag
    Dmel_CG3073
    See related
    AllianceGenome:FB:FBgn0027296
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG3073; Dmel\CG3073; l(1)G0144
    Summary
    Contributes to Rab geranylgeranyltransferase activity. Involved in sensory organ development. Located in cytoplasm. Part of Rab-protein geranylgeranyltransferase complex. Is expressed in external sensory organ precursor cell and organism. Orthologous to human PTAR1 (protein prenyltransferase alpha subunit repeat containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See temp in Genome Data Viewer
    Location:
    2F2-2F2; 1-0.9 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (2260207..2262515, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (2154240..2156548, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45480

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Deep-fried signaling: tempura gets notch cooking. Sedwick C. PLoS Biol, 2014 Jan. PMID 24492884, Free PMC Article
    2. Drosophila Tempura, a novel protein prenyltransferase α subunit, regulates notch signaling via Rab1 and Rab11. Charng WL, et al. PLoS Biol, 2014 Jan. PMID 24492843, Free PMC Article
    3. Integration of Drosophila and Human Genetics to Understand Notch Signaling Related Diseases. Salazar JL, et al. Adv Exp Med Biol, 2018. PMID 30030826, Free PMC Article
    4. A Genetic Screen for Genes That Impact Peroxisomes in Drosophila Identifies Candidate Genes for Human Disease. Graves HK, et al. G3 (Bethesda), 2020 Jan 7. PMID 31767637, Free PMC Article
    5. Neutral Competition for Drosophila Follicle and Cyst Stem Cell Niches Requires Vesicle Trafficking Genes. Cook MS, et al. Genetics, 2017 Jul. PMID 28512187, Free PMC Article

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Drosophila Tempura, a novel protein prenyltransferase alpha subunit, regulates notch signaling via Rab1 and Rab11.
      Title: Drosophila Tempura, a novel protein prenyltransferase α subunit, regulates notch signaling via Rab1 and Rab11.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    contributes_to Rab geranylgeranyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    contributes_to Rab geranylgeranyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein prenyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein prenylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in sensory organ development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Rab-protein geranylgeranyltransferase complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tempura
    Names
    CG3073-PA
    CG3073-PB
    lethal (1) G0144
    temp-PA
    temp-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      2260207..2262515 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_130636.3 → NP_569992.1  tempura, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_569992.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W501
      Related
      FBpp0070398
      Conserved Domains (1) summary
      pfam01239
      Location:168 → 195
      PPTA; Protein prenyltransferase alpha subunit repeat

    2. NM_001297889.1 → NP_001284818.1  tempura, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001284818.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W501
      Conserved Domains (1) summary
      pfam01239
      Location:168 → 195
      PPTA; Protein prenyltransferase alpha subunit repeat
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W501 Q9W501

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