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    CARPA Carbonic anhydrase-related protein A [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31687, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CARPAprovided by FlyBase
    Official Full Name
    Carbonic anhydrase-related protein Aprovided by FlyBase
    Primary source
    FLYBASE:FBgn0029962
    Locus tag
    Dmel_CG1402
    See related
    AllianceGenome:FB:FBgn0029962
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG1402; Dmel\CG1402
    Summary
    Predicted to enable hydro-lyase activity. Predicted to be involved in one-carbon metabolic process. Is expressed in adult head. Orthologous to human CA10 (carbonic anhydrase 10) and CA11 (carbonic anhydrase 11). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CARPA in Genome Data Viewer
    Location:
    7C1-7C1; 1-21 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (7826197..7842679)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (7720230..7736712)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Carbonic anhydrases and anion transport in mosquito midgut pH regulation. Linser PJ, et al. J Exp Biol, 2009 Jun. PMID 19448076, Free PMC Article
    2. The lack of recombination drives the fixation of transposable elements on the fourth chromosome of Drosophila melanogaster. Bartolomé C, et al. Genet Res, 2004 Apr. PMID 15219154
    3. Temporal evolution of single-cell transcriptomes of Drosophila olfactory projection neurons. Xie Q, et al. Elife, 2021 Jan 11. PMID 33427646, Free PMC Article
    4. The Genetic Basis for Variation in Sensitivity to Lead Toxicity in Drosophila melanogaster. Zhou S, et al. Environ Health Perspect, 2016 Jul. PMID 26859824, Free PMC Article
    5. Genome-wide association analysis of oxidative stress resistance in Drosophila melanogaster. Weber AL, et al. PLoS One, 2012. PMID 22496853, Free PMC Article

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables carbonate dehydratase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydro-lyase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    carbonic anhydrase-related protein A
    Names
    CARPA-PB
    CARPA-PC
    CG1402-PB
    CG1402-PC
    NP_001284986.1
    NP_572407.3

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      7826197..7842679
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001298057.1 → NP_001284986.1  carbonic anhydrase-related protein A, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001284986.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q29QI5, Q9W3P7
      Conserved Domains (1) summary
      cd03121
      Location:46 → 300
      alpha_CARP_X_XI_like; Carbonic anhydrase alpha related protein: groups X, XI and related proteins. This subgroup contains carbonic anhydrase related proteins (CARPs) X and XI, which have been implicated in various biological processes of the central nervous system. CARPs are ...

    2. NM_132179.4 → NP_572407.3  carbonic anhydrase-related protein A, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572407.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q29QI5, Q9W3P7
      Conserved Domains (1) summary
      cd03121
      Location:46 → 300
      alpha_CARP_X_XI_like; Carbonic anhydrase alpha related protein: groups X, XI and related proteins. This subgroup contains carbonic anhydrase related proteins (CARPs) X and XI, which have been implicated in various biological processes of the central nervous system. CARPs are ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W3P7 Q9W3P7

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