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    CG33178 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 318913, updated on 27-Dec-2024

    Summary

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    Official Symbol
    CG33178provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0053178
    Locus tag
    Dmel_CG33178
    See related
    AllianceGenome:FB:FBgn0053178
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:RH14671; CG5579; Dmel\CG33178
    Summary
    Predicted to enable glutathione peroxidase activity and glutathione transferase activity. Predicted to be involved in glutathione metabolic process. Predicted to be located in mitochondrial outer membrane. Is expressed in adult head; embryonic head sensory system; and larval labral sensory complex. Orthologous to several human genes including MGST1 (microsomal glutathione S-transferase 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG33178 in Genome Data Viewer
    Location:
    13A9-13A9; 1-49 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (15082827..15084017)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (14976860..14978050)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44662 Neighboring gene long non-coding RNA:CR44661 Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR44960 Neighboring gene Cytochrome c oxidase copper chaperone COX17 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A combined computational strategy of sequence and structural analysis predicts the existence of a functional eicosanoid pathway in Drosophila melanogaster. Scarpati M, et al. PLoS One, 2019. PMID 30753230, Free PMC Article
    2. Analyses of nuclearly encoded mitochondrial genes suggest gene duplication as a mechanism for resolving intralocus sexually antagonistic conflict in Drosophila. Gallach M, et al. Genome Biol Evol, 2010. PMID 21037198, Free PMC Article
    3. RNA-seq reveals post-transcriptional regulation of Drosophila insulin-like peptide dilp8 and the neuropeptide-like precursor Nplp2 by the exoribonuclease Pacman/XRN1. Jones CI, et al. Nucleic Acids Res, 2016 Jan 8. PMID 26656493, Free PMC Article
    4. Gene expression profiling of brakeless mutant Drosophila embryos. Crona F, et al. Data Brief, 2015 Dec. PMID 26509186, Free PMC Article
    5. Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions. Erives AJ. Dev Genes Evol, 2015 Sep. PMID 26173873, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables glutathione peroxidase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables glutathione transferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in glutathione metabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrial outer membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG33178-PA
    CG33178-PB
    CG33178-PC
    NP_001285263.1
    NP_001285264.1
    NP_788904.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      15082827..15084017
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001298335.1 → NP_001285264.1  uncharacterized protein Dmel_CG33178, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285264.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SY97
      Conserved Domains (1) summary
      pfam01124
      Location:29 → 159
      MAPEG; MAPEG family

    2. NM_001298334.1 → NP_001285263.1  uncharacterized protein Dmel_CG33178, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285263.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      X2JF29
      Conserved Domains (1) summary
      pfam01124
      Location:29 → 171
      MAPEG; MAPEG family

    3. NM_176731.2 → NP_788904.1  uncharacterized protein Dmel_CG33178, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788904.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SY97
      Related
      FBpp0073780
      Conserved Domains (1) summary
      pfam01124
      Location:29 → 159
      MAPEG; MAPEG family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8SY97 Q8SY97
    X2JF29 X2JF29

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