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    mRpL42 mitochondrial ribosomal protein L42 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36050, updated on 9-Dec-2024

    Summary

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    Official Symbol
    mRpL42provided by FlyBase
    Official Full Name
    mitochondrial ribosomal protein L42provided by FlyBase
    Primary source
    FLYBASE:FBgn0033480
    Locus tag
    Dmel_CG12921
    See related
    AllianceGenome:FB:FBgn0033480
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:RE72116; CG12921; Dmel\CG12921; MRP-S32; MRPL31; mRpS32
    Summary
    Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Predicted to be part of mitochondrial large ribosomal subunit and mitochondrial small ribosomal subunit. Is expressed in adult head; adult heart; embryonic/larval midgut; and organism. Orthologous to human MRPL42 (mitochondrial ribosomal protein L42). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See mRpL42 in Genome Data Viewer
    Location:
    46E1-46E1; 2-62 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (10066650..10067242)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (5954155..5954747)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene magu Neighboring gene Defensin Neighboring gene Phosphatidylinositol glycan anchor biosynthesis class N Neighboring gene Cdc2-related kinase Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene snoRNA:Orphan H/ACA box 7 Neighboring gene eiger

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structural compensation for the deficit of rRNA with proteins in the mammalian mitochondrial ribosome. Systematic analysis of protein components of the large ribosomal subunit from mammalian mitochondria. Suzuki T, et al. J Biol Chem, 2001 Jun 15. PMID 11279069
    2. The small subunit of the mammalian mitochondrial ribosome. Identification of the full complement of ribosomal proteins present. Cavdar Koc E, et al. J Biol Chem, 2001 Jun 1. PMID 11279123
    3. False negative rates in Drosophila cell-based RNAi screens: a case study. Booker M, et al. BMC Genomics, 2011 Jan 20. PMID 21251254, Free PMC Article
    4. The SIN3 deacetylase complex represses genes encoding mitochondrial proteins: implications for the regulation of energy metabolism. Pile LA, et al. J Biol Chem, 2003 Sep 26. PMID 12865422
    5. The ribosomal protein genes and Minute loci of Drosophila melanogaster. Marygold SJ, et al. Genome Biol, 2007. PMID 17927810, Free PMC Article

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables structural constituent of ribosome TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mitochondrial translation TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of mitochondrial large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of mitochondrial large ribosomal subunit TAS
    Traceable Author Statement
    more info
    		 PubMed 
    part_of mitochondrial small ribosomal subunit ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mitochondrial ribosomal protein L42
    Names
    CG12921-PA
    CG12921-PB
    mRpL42-PA
    mRpL42-PB
    mitochondrial ribosomal protein S32

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      10066650..10067242
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_078949.4 → NP_523673.1  mitochondrial ribosomal protein L42, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_523673.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7K0A0
      Related
      FBpp0087491
      Conserved Domains (1) summary
      pfam10210
      Location:29 → 121
      MRP-S32; Mitochondrial 28S ribosomal protein S32

    2. NM_001201970.2 → NP_001188899.1  mitochondrial ribosomal protein L42, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001188899.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7K0A0
      Conserved Domains (1) summary
      pfam10210
      Location:29 → 121
      MRP-S32; Mitochondrial 28S ribosomal protein S32
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7K0A0 Q7K0A0

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